Dynamics of thermoelastic expansion for native and coagulated ex-vivo bovine liver tissues

被引:0
|
作者
Soroushian, Behrouz [1 ]
Whelan, William M. [2 ]
Kolios, Michael C. [1 ]
机构
[1] Ryerson Univ, Dept Phys, Toronto, ON, Canada
[2] Univ PEI, Dept Phys, Charlottetown, PE, Canada
基金
加拿大创新基金会; 加拿大自然科学与工程研究理事会; 加拿大健康研究院;
关键词
optoacoustic imaging; monitoring thermal therapy; laser interferometry; surface displacement measurement; thermoelastic expansion; Gruneisen parameter;
D O I
10.1117/12.843042
中图分类号
O43 [光学];
学科分类号
070207 ; 0803 ;
摘要
Dynamics of the thermoelastic expansion of native and coagulated ex-vivo bovine liver tissues after their irradiation by short laser pulses were studied. The differences in optical and thermo-mechanical properties of the native and coagulated samples such as their Gruneisen coefficient and optical attenuation depth were quantitatively determined. It was found that for coagulated ex-vivo bovine liver samples, the optical attenuation depth decrease by an average of 47%. Also significant differences were observed in the dynamics of thermoelastic expansion of the tissue surface. These differences can be potentially linked to differences in thermo-mechanical properties between native and coagulated samples. The changes in these properties may be used to understand the mechanisms of contrast between coagulated and non-coagulated tissues in optoacoustic imaging.
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页数:4
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