IRON-DEPLETION PREVENTS BIOFILM FORMATION IN PSEUDOMONAS AERUGINOSA THROUGH TWITCHING MOTILITY AND QUORUM SENSING

被引:18
|
作者
Cai, Yun [1 ]
Wang, Rui [1 ]
An, Mao-Mao [1 ]
Liang, Bei-Bei [1 ]
机构
[1] Peoples Liberat Army Gen Hosp, Dept Clin Pharmacol, Beijing 100080, Peoples R China
关键词
iron; biofilm; twitching motility; quorum sensing; CYSTIC-FIBROSIS; IV PILI; COLONIZATION; EXPRESSION; SIGNAL;
D O I
10.1590/S1517-83822010000100008
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
Influence of iron-depletion on twitching motility and quorum sensing (QS) system in P. aeruginosa was evaluated. The results demonstrated iron-depletion can retard biofilm formation and increase the twitching motility and expression of QS-related genes, suggesting a potential interaction between twitching motility and QS system in P. aeruginosa biofilm formation.
引用
收藏
页码:37 / 41
页数:5
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