Evidence for the Natural Toxins from the Mushroom Trogia venenata as a Cause of Sudden Unexpected Death in Yunnan Province, China

被引:52
|
作者
Zhou, Zhong-Yu [2 ,4 ]
Shi, Guo-Qing [1 ]
Fontaine, Robert [1 ,3 ]
Wei, Kun [2 ]
Feng, Tao [2 ]
Wang, Fang [2 ]
Wang, Gang-Qiang [2 ]
Qu, Yan [2 ]
Li, Zheng-Hui [2 ]
Dong, Ze-Jun [2 ]
Zhu, Hua-Jie [2 ]
Yang, Zhu-Liang [2 ]
Zeng, Guang [1 ]
Liu, Ji-Kai [2 ]
机构
[1] Chinese Ctr Dis Control & Prevent, Beijing 100050, Peoples R China
[2] Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources W China, Kunming 650204, Peoples R China
[3] US Ctr Dis Control & Prevent, Atlanta, GA 30333 USA
[4] Chinese Acad Sci, S China Bot Garden, Guangzhou 510650, Guangdong, Peoples R China
关键词
amino acids; mushrooms; natural products; toxicology; GAMMA-GUANIDINOBUTYRIC ACID; METHYLENECYCLOPROPYLGLYCINE;
D O I
10.1002/anie.201106502
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Life saver: Two unusual and toxic amino acids, 2R-amino-4S-hydroxy-5- hexynoic acid (red, see scheme) and 2R-amino-5-hexynoic acid (blue) have been isolated from the fruiting bodies of the mushroom Trogia venenata. Toxicology studies suggest that these compounds may be the cause of Sudden Unexplained Death (SUD) in Yunnan Province, China. Copyright © 2012 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
引用
收藏
页码:2368 / 2370
页数:3
相关论文
共 50 条
  • [31] Research on the Impact of Farmland Transfer on Rural Household Consumption: Evidence from Yunnan Province, China
    Hong, Mingyong
    Lou, Lei
    [J]. LAND, 2022, 11 (12)
  • [32] Molecular evidence of the spotted fever group Rickettsiae in ticks from Yunnan Province, Southwest China
    Hao Liu
    Xiaotong Liang
    Haijun Wang
    Xiutao Sun
    Xue Bai
    Bo Hu
    Ning Shi
    Nina Wang
    Xuelian Zhang
    Liangzhong Huang
    Jiedan Liao
    Fuqiang Huang
    Haoji Zhang
    Xingkui Si
    Shujian Huang
    Ningyi Jin
    Quan Liu
    Lixia Li
    [J]. Experimental and Applied Acarology, 2020, 80 : 339 - 348
  • [33] HEMORRHAGES FROM CAPILLARY TELANGIECTASIS IN THE BRAIN-STEM - A POSSIBLE CAUSE OF SUDDEN NATURAL DEATH
    MISSLIWETZ, J
    REITER, C
    [J]. ZEITSCHRIFT FUR RECHTSMEDIZIN-JOURNAL OF LEGAL MEDICINE, 1984, 92 (01): : 59 - 65
  • [34] Sudden unexpected death in infancy associated with maltreatment: evidence from long term follow up of siblings
    Stanton, AN
    [J]. ARCHIVES OF DISEASE IN CHILDHOOD, 2003, 88 (08) : 699 - 701
  • [35] Carbon and hydrogen isotopic characteristics of natural gases from the Luliang and Baoshan basins in Yunnan Province, China
    Yongchang Xu
    Wenhui Liu
    Ping Shen
    Wanchun Wang
    Xiaofeng Wang
    Yaomin Tenger
    Ruobin Yan
    [J]. Science in China Series D: Earth Sciences, 2006, 49 : 938 - 946
  • [36] Amentotaxus x hybridia (Taxaceae), a new natural Amentotaxus hybrid from southeast Yunnan province, China
    Gao, Lian-Ming
    Zhang, Gui-Liang
    Mo, Zhi-Qiong
    Thomas, Philip
    [J]. PHYTOKEYS, 2023, (226) : 101 - 108
  • [37] Assessment of potential human health risk of trace element in wild edible mushroom species collected from Yunnan Province, China
    Fu, Zhiqiu
    Liu, Gang
    Wang, Luxiang
    [J]. ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH, 2020, 27 (23) : 29218 - 29227
  • [38] Assessment of potential human health risk of trace element in wild edible mushroom species collected from Yunnan Province, China
    Zhiqiu Fu
    Gang Liu
    Luxiang Wang
    [J]. Environmental Science and Pollution Research, 2020, 27 : 29218 - 29227
  • [39] Carbon and hydrogen isotopic characteristics of natural gases from the Luliang and Baoshan basins in Yunnan Province, China
    XU Yongchang1
    2. Research Institute of Petroleum Exploration and Production
    3. South Branch of Petroleum Exploration and Production Company
    [J]. Science China Earth Sciences, 2006, (09) : 938 - 946
  • [40] Carbon and hydrogen isotopic characteristics of natural gases from the Luliang and Baoshan basins in Yunnan Province, China
    Xu Yongchang
    Liu Wenhui
    Shen Ping
    Wang Wanchun
    Wang Xiaofeng
    Tenger
    Yan Yaomin
    Liu Ruobin
    [J]. SCIENCE IN CHINA SERIES D-EARTH SCIENCES, 2006, 49 (09): : 938 - 946