An efficient one-pot synthesis of 2-hydroxyalkyl dithiocarbamates

被引:24
|
作者
Cui, JL [1 ]
Ge, ZM [1 ]
Cheng, TM [1 ]
Li, RT [1 ]
机构
[1] Peking Univ, Sch Pharmaceut Sci, Dept Biol Chem, Beijing 100083, Haidian Dist, Peoples R China
关键词
2-hydroxyalkyl dithiocarbamate; ring opening of epoxide; regioselective reaction; anhydrous potassium phosphate; carbon disulfide;
D O I
10.1081/SCC-120021023
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
In the presence of anhydrous potassium phosphate, epoxides reacted with carbon disulfide and primary or secondary amines in acetone to give the corresponding 2-hydroxyalkyl dithiocarbamates regioselectively in moderate to good yield.
引用
收藏
页码:1969 / 1976
页数:8
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