Cloning and sequencing of a human cDNA encoding endothelial P2Y(1) purinoceptor

被引：83
|
作者：
Leon, C [1 ]
Vial, C [1 ]
Cazenave, JP [1 ]
Gachet, C [1 ]
机构：
[1] ETABLISSEMENT TRANSFUS SANGUINE STRASBOURG,INSERM,U311,F-67065 STRASBOURG,FRANCE
来源：
GENE | 1996年 / 171卷 / 02期
关键词：
ATP receptor; G-protein-coupled receptor; nucleotide; endothelial cells;
D O I：
10.1016/0378-1119(96)00027-3
中图分类号：
Q3 [遗传学];
学科分类号：
071007 ; 090102 ;
摘要：
We have cloned and sequenced a 3055-bp human placenta cDNA encoding a P-2 purinoceptor. An identical receptor has also been found in human saphenous vein endothelial cells. Comparison of the deduced amino acid (aa) sequence to those of previously described P2Y(1) purinoceptors revealed greater than 95% aa identity with the rat and mouse counterparts, and 83% with the chick P2Y(1) purinoceptor. Northern blot experiments revealed two mRNAs of 7.5 and 4.6 kb whose expression varies according to the tissue examined.
引用
收藏
页码：295 / 297
页数：3
相关论文
共 50 条
  • [21] The P2Y purinoceptor, P2Y14R, promotes AHR in an animal model of asthma
    Karcz, Tadeusz
    Nakano, Hideki
    Jacobson, Kenneth
    Cook, Donald
    JOURNAL OF IMMUNOLOGY, 2018, 200 (01):
  • [22] Cloning and sequencing of cDNA encoding for a human sperm antigen involved in fertilization
    Zhu, XL
    Naz, RK
    MOLECULAR REPRODUCTION AND DEVELOPMENT, 1998, 51 (02) : 176 - 183
  • [23] Cloning and sequencing of a human cDNA encoding ornithine decarboxylase antizyme inhibitor
    Koguchi, K
    Kobayashi, S
    Hayashi, T
    Matsufuji, S
    Murakami, Y
    Hayashi, S
    BIOCHIMICA ET BIOPHYSICA ACTA-GENE STRUCTURE AND EXPRESSION, 1997, 1353 (03): : 209 - 216
  • [24] Cloning, functional expression and tissue distribution of the human P2Y(6) receptor
    Communi, D
    Parmentier, M
    Boeynaems, JM
    BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1996, 222 (02) : 303 - 308
  • [25] Cloning of a human heptahelical receptor closely related to the P2Y(5) receptor
    Janssens, R
    Boeynaems, JM
    Godart, M
    Communi, D
    BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1997, 236 (01) : 106 - 112
  • [26] Cloning and chromosomal localization of the human P2Y1 purinoceptor (vol 218, pg 783, 1996)
    Ayyanathan, K
    Webb, TE
    Sandhu, AK
    Athwal, RS
    Barnard, EA
    Kunapuli, SP
    BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1996, 221 (02) : 489 - 489
  • [27] CLONING AND SEQUENCING OF A CDNA-ENCODING MOUSE STROMELYSIN-1
    HAMMANI, K
    HENRIET, P
    EECKHOUT, Y
    GENE, 1992, 120 (02) : 321 - 322
  • [28] DUAL REGULATION OF PANCREATIC VASCULAR TONE BY P2X AND P2Y PURINOCEPTOR SUBTYPES
    HILLAIREBUYS, D
    CHAPAL, J
    PETIT, P
    LOUBATIERESMARIANI, MM
    EUROPEAN JOURNAL OF PHARMACOLOGY, 1991, 199 (03) : 309 - 314
  • [29] HUMAN SELENOPROTEIN-P - CLONING AND SEQUENCING OF A CDNA CLONE
    HILL, KE
    LLOYD, RS
    BURK, RF
    FASEB JOURNAL, 1992, 6 (04): : A1365 - A1365
  • [30] Cloning and sequencing of a human cDNA encoding a putative transcription factor containing a bromodomain
    Nielsen, MS
    Petersen, CM
    Gliemann, J
    Madsen, P
    BIOCHIMICA ET BIOPHYSICA ACTA-GENE STRUCTURE AND EXPRESSION, 1996, 1306 (01): : 14 - 16
12345