Cloning and sequencing of a human cDNA encoding a putative transcription factor containing a bromodomain

被引：9
|
作者：
Nielsen, MS
Petersen, CM
Gliemann, J
Madsen, P
机构：
[1] Department of Medical Biochemistry, University of Aarhus, Bldg. 170, DK-8000 Aarhus C, Ole Worms Allé
来源：
BIOCHIMICA ET BIOPHYSICA ACTA-GENE STRUCTURE AND EXPRESSION | 1996年 / 1306卷 / 01期
关键词：
sequencing; bromodomain; transcription factor;
D O I：
10.1016/0167-4781(95)00239-1
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
A 2985 bp cDNA was isolated from a Lambda Zap Express library and sequenced. The cDNA appeared to represent a previously unknown gene that encodes an acidic 757 amino acid protein containing a bromodomain, several potential sites for phosphorylation by casein kinase-II and small proline-rich segments. The results suggest that the encoded protein might be a novel transcription factor.
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收藏
页码：14 / 16
页数：3
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