Microwave-assisted solid-phase Ugi four-component condensations

被引：84
|
作者：
Hoel, AML [1 ]
Nielsen, J [1 ]
机构：
[1] Tech Univ Denmark, Dept Organ Chem, DK-2800 Lyngby, Denmark
来源：
TETRAHEDRON LETTERS | 1999年 / 40卷 / 20期
关键词：
solid-phase synthesis; Ugi-Passerini reactions; microwave heating; combinatorial chemistry;
D O I：
10.1016/S0040-4039(99)00616-4
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
An 18-member library was constructed from 2 isocyanides, 3 aldehydes and 3 carboxylic acids via microwave-assisted solid-phase Ugi reactions on TentaGel S RAM. Products of high purity were obtained in moderate to excellent yields after reaction times of 5 minutes or less (irradiation at 60W). (C) 1999 Elsevier Science Ltd. All rights reserved.
引用
下载
收藏
页码：3941 / 3944
页数：4
相关论文
共 50 条
  • [1] Solid-phase synthesis of PNA monomer by Ugi four-component condensation
    Wang, WH
    Zou, XM
    Zhang, X
    Fu, YQ
    Xu, P
    CHINESE CHEMICAL LETTERS, 2005, 16 (05) : 585 - 588
  • [2] Solid-phase Synthesis of PNA Monomer by Ugi Four-component Condensation Reaction
    Wen Hao WANG
    Chinese Chemical Letters, 2005, (05) : 585 - 588
  • [3] Direct synthesis of the arylboronic acid analogues of phenylglycine via microwave-assisted four-component Ugi reaction
    Lian, Ru-Ching
    Lin, Meng-Hsuan
    Liao, Pin-Hsuan
    Fu, Jia-Jie
    Wu, Meng-Ju
    Wu, Yang-Chang
    Chang, Fang-Rong
    Wu, Chin-Chung
    Pan, Po-Shen
    TETRAHEDRON, 2014, 70 (09) : 1800 - 1804
  • [4] Solid-phase synthesis of potential protein tyrosine phosphatase inhibitors via the UGI four-component condensation
    Li, ZG
    Yeo, SL
    Pallen, CJ
    Ganesan, A
    BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 1998, 8 (18) : 2443 - 2446
  • [5] Microwave-assisted solid-phase synthesis of peptoids
    Olivos, HJ
    Alluri, PG
    Reddy, MM
    Salony, D
    Kodadek, T
    ORGANIC LETTERS, 2002, 4 (23) : 4057 - 4059
  • [6] Microwave-assisted solid-phase synthesis of phthalimides
    Martin, B
    Sekljic, H
    Chassaing, C
    ORGANIC LETTERS, 2003, 5 (11) : 1851 - 1853
  • [7] Microwave-Assisted Solid-Phase Synthesis of Antifreeze Glycopeptides
    Izumi, Ryukou
    Matsushita, Takahiko
    Fujitani, Naoki
    Naruchi, Kentaro
    Shimizu, Hiroki
    Tsuda, Sakae
    Hinou, Hiroshi
    Nishimura, Shin-Ichiro
    CHEMISTRY-A EUROPEAN JOURNAL, 2013, 19 (12) : 3913 - 3920
  • [8] Rapid microwave-assisted Suzuki coupling on solid-phase
    Larhed, M
    Lindeberg, G
    Hallberg, A
    TETRAHEDRON LETTERS, 1996, 37 (45) : 8219 - 8222
  • [9] Solid-phase and microwave-assisted synthesis of ligands for lanthanides
    Hopper, Lauren
    Allen, Matthew J.
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2013, 245
  • [10] Microwave-assisted solid-phase synthesis of hydantoin derivatives
    Colacino, Evelina
    Lamaty, Frederic
    Martinez, Jean
    Parrot, Isabelle
    TETRAHEDRON LETTERS, 2007, 48 (30) : 5317 - 5320
12345