One-pot Sonogashira coupling, hydroamination of alkyne and intramolecular C-H arylation reactions toward the synthesis of indole-fused benzosultams

被引：7

作者：

Debnath, Sudarshan ^{[1
]}

Mondal, Shovan ^{[1
]}

机构：

[1] Syamsundar Coll, Dept Chem, Shyamsundar 713424, India

来源：

TETRAHEDRON LETTERS | 2018年 / 59卷 / 23期

关键词：

Benzosultams; Sonogashira coupling; Hydroamination; C-H arylation; Indole; REGIOSELECTIVE SYNTHESIS; CYCLIZATION; SULTAMS; INHIBITORS; ALKENES; AMINE;

D O I：

10.1016/j.tetlet.2018.04.081

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A one-pot Sonogashira coupling, hydroamination of alkyne and C-H arylation reactions for the synthesis of indole-fused benzosultams are described. This method allows access to a variety of indole-fused seven membered benzosultams in good to excellent yields. The free indolyl nitrogen containing indole-fused benzosultams are also prepared by this method. The structures of the synthesized compounds are confirmed by single crystal XRD studies. (C) 2018 Elsevier Ltd. All rights reserved.

引用

页码：2260 / 2263

页数：4

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