Catalytic Electrochemical C-H Iodination and One-Pot Arylation by ON/OFF Switching of Electric Current

被引：100
|
作者：
Aiso, Hiroko [1 ]
Kochi, Takuya [1 ]
Mutsutani, Hitoshi [1 ]
Tanabe, Takamasa [1 ]
Nishiyama, Shigeru [1 ]
Kakiuchi, Fumitoshi [1 ]
机构：
[1] Keio Univ, Dept Chem, Fac Sci & Technol, Kohoku Ku, Yokohama, Kanagawa 2238522, Japan
来源：
JOURNAL OF ORGANIC CHEMISTRY | 2012年 / 77卷 / 17期
关键词：
CROSS-COUPLING REACTIONS; AROMATIC-COMPOUNDS; BOND-CLEAVAGE; NOBEL LECTURE; PALLADIUM; HALOGENATION; OXIDATION; ARENES; ACIDS; FUNCTIONALIZATION;
D O I：
10.1021/jo3012286
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Palladium-catalyzed electrochemical iodination and one-pot arylation of arylpyridines are described. Ortho-selective C-H iodination proceeded via dual activation of each substrate by a palladium catalyst and an electrode. Various aryl groups were introduced at the ortho positions of arylpyridines by ON/OFF switching of two different catalytic cycles using the same palladium catalyst in a one-pot fashion.
引用
收藏
页码：7718 / 7724
页数：7
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