Dupilumab in Patients with Corticosteroid-Dependent Severe Asthma: Efficacy and Safety Results from the Randomized, Double-Blind, Placebo-Controlled Phase 3 LIBERTY ASTHMA VENTURE Study

被引:0
|
作者
Rabe, K. F. [1 ,2 ]
Nair, P. K. [3 ,4 ]
Brusselle, G. G. [5 ]
Maspero, J. F. [6 ]
Castro, M. [7 ]
Zhu, H. [8 ]
Staudinger, H. [8 ]
Pirozzi, G. [8 ]
Antoni, C. [8 ]
Amin, N. [9 ]
Ruddy, M. [9 ]
Akinlade, B. [9 ]
Khan, A. [10 ]
Chao, J. [9 ]
Graham, N. M. [9 ]
Teper, A. [8 ]
机构
[1] LungenClin Grosshansdorf, Kiel, Germany
[2] Univ Kiel, Kiel, Germany
[3] McMaster Univ, Hamilton, ON, Canada
[4] St Josephs Healthcare, Hamilton, ON, Canada
[5] Ghent Univ Hosp, Ghent, Belgium
[6] Fdn CIDEA, Buenos Aires, DF, Argentina
[7] Washington Univ, Sch Med, St Louis, MO USA
[8] Sanofi, Bridgewater, NJ USA
[9] Regeneron Pharmaceut Inc, 777 Old Saw Mill River Rd, Tarrytown, NY 10591 USA
[10] Sanofi, Chilly Mazarin, France
关键词
D O I
暂无
中图分类号
R4 [临床医学];
学科分类号
1002 ; 100602 ;
摘要
A7712
引用
收藏
页数:2
相关论文
共 50 条
  • [31] A randomized, double-blind placebo-controlled study of the safety of apadenoson in subjects with mild or moderate asthma
    Williams, S. P.
    Mcardle, J. R.
    Colice, G.
    Lankford, A.
    Kajdasz, D. K.
    Reed, C. R.
    EUROPEAN HEART JOURNAL SUPPLEMENTS, 2011, 13 (0A) : A95 - A96
  • [32] Efficacy and safety of oxycodone DETERx: results of a randomized, double-blind, placebo-controlled phase III study
    Kopecky, E.
    O'Connor, M.
    Varanasi, R.
    Saim, S.
    Fleming, A.
    JOURNAL OF PAIN, 2015, 16 (04): : S87 - S87
  • [33] A RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED STUDY TO EVALUATE THE EFFECT OF DUPILUMAB ON AIRWAY REMODELING IN PATIENTS WITH UNCONTROLLED, MODERATE-TO-SEVERE ASTHMA: THE VESTIGE STUDY
    Gomez, Lucia De Prado
    Castro, Mario
    Papi, Alberto
    Ardeleanu, Marius
    Deniz, Yamo
    Rowe, Paul
    CHEST, 2021, 160 (04) : 1492A - 1495A
  • [34] Efficacy and safety of tralokinumab in patients with severe uncontrolled asthma: a randomised, double-blind, placebo-controlled, phase 2b trial
    Brightling, Christopher E.
    Chanez, Pascal
    Leigh, Richard
    O'Byrne, Paul M.
    Korn, Stephanie
    She, Dewei
    May, Richard D.
    Streicher, Katie
    Ranade, Koustubh
    Piper, Edward
    LANCET RESPIRATORY MEDICINE, 2015, 3 (09): : 692 - 701
  • [35] SOURCE: a phase 3, multicentre, randomized, double-blind, placebo-controlled, parallel group trial to evaluate the efficacy and safety of tezepelumab in reducing oral corticosteroid use in adults with oral corticosteroid dependent asthma
    Wechsler, Michael E.
    Colice, Gene
    Griffiths, Janet M.
    Almqvist, Gun
    Skarby, Tor
    Piechowiak, Teresa
    Kaur, Primal
    Bowen, Karin
    Hellqvist, Asa
    Mo, May
    Garcia Gil, Esther
    RESPIRATORY RESEARCH, 2020, 21 (01)
  • [36] Effect of Tezepelumab in Oral Corticosteroid-Dependent Patients with Severe Asthma: Results From the Phase 3 NAVIGATOR Study
    Menzies-Gow, A.
    Brightling, C. E.
    Ambrose, C. S.
    Cook, B.
    Hellgvist, A.
    Ackert, J. Llanos
    Colice, G.
    Wechsler, M.
    AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 2021, 203 (09)
  • [37] SOURCE: a phase 3, multicentre, randomized, double-blind, placebo-controlled, parallel group trial to evaluate the efficacy and safety of tezepelumab in reducing oral corticosteroid use in adults with oral corticosteroid dependent asthma
    Michael E. Wechsler
    Gene Colice
    Janet M. Griffiths
    Gun Almqvist
    Tor Skärby
    Teresa Piechowiak
    Primal Kaur
    Karin Bowen
    Åsa Hellqvist
    May Mo
    Esther Garcia Gil
    Respiratory Research, 21
  • [38] Erenumab treatment for migraine prevention in Japanese patients: Efficacy and safety results from a Phase 3, randomized, double-blind, placebo-controlled study
    Takeshima, Takao
    Sakai, Fumihiko
    Hirata, Koichi
    Imai, Noboru
    Matsumori, Yasuhiko
    Yoshida, Ryuji
    Peng, Cheng
    Cheng, Sunfa
    Mikol, Daniel D.
    HEADACHE, 2021, 61 (06): : 927 - 935
  • [39] Effects of Dupilumab on Mucus Plugging and Ventilation Defects in Patients with Moderate-to-Severe Asthma: A Randomized, Double-Blind, Placebo-Controlled Trial
    Svenningsen, Sarah
    Kjarsgaard, Melanie
    Haider, Ehsan
    Venegas, Carmen
    Konyer, Norman
    Friedlander, Yonni
    Nasir, Neha
    Boylan, Colm
    Kirby, Miranda
    Nair, Parameswaran
    AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 2023, 208 (09) : 995 - 997
  • [40] Efficacy and Safety of Reparixin in Patients with Severe COVID-19 Pneumonia: A Phase 3, Randomized, Double-Blind Placebo-Controlled Study
    Piemonti, Lorenzo
    Landoni, Giovanni
    Voza, Antonio
    Puoti, Massimo
    Gentile, Ivan
    Coppola, Nicola
    Nava, Stefano
    Mattei, Alessia
    Marinangeli, Franco
    Marchetti, Giulia
    Bonfanti, Paolo
    Mastroianni, Claudio Maria
    Bassetti, Matteo
    Crisafulli, Ernesto
    Grossi, Paolo Antonio
    Zangrillo, Alberto
    Desai, Antonio
    Merli, Marco
    Foggia, Maria
    Carpano, Marco
    Schiavoni, Lorenzo
    Monforte, Antonella D'Arminio
    Bisi, Luca
    Russo, Gianluca
    Busti, Fabiana
    Rovelli, Cristina
    Perrotta, Elisabetta
    Goisis, Giovanni
    Gavioli, Elizabeth M.
    Toya, Sophie
    De Pizzol, Maria
    Mantelli, Flavio
    Allegretti, Marcello
    Minnella, Enrico Maria
    INFECTIOUS DISEASES AND THERAPY, 2023, 12 (10) : 2437 - 2456