A RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED STUDY TO EVALUATE THE EFFECT OF DUPILUMAB ON AIRWAY REMODELING IN PATIENTS WITH UNCONTROLLED, MODERATE-TO-SEVERE ASTHMA: THE VESTIGE STUDY

被引：1
|
作者：
Gomez, Lucia De Prado
Castro, Mario
Papi, Alberto
Ardeleanu, Marius
Deniz, Yamo
Rowe, Paul
机构：
来源：
CHEST | 2021年 / 160卷 / 04期
关键词：
D O I：
10.1016/j.chest.2021.07.1367
中图分类号：
R4 [临床医学];
学科分类号：
1002 ; 100602 ;
摘要：
引用
收藏
页码：1492A / 1495A
页数：4
相关论文
共 50 条
  • [1] Effect of Tezepelumab on Airway Inflammation in Patients with Moderate-to-Severe Uncontrolled Asthma: A Phase 2, Randomized, Double-Blind, Placebo-Controlled Study (CASCADE)
    Diver, S. E.
    Khalfaoui, L.
    Emson, C.
    Wenzel, S. E.
    Menzies-Gow, A.
    Wechsler, M.
    Johnston, J.
    Downie, J.
    Parnes, J. R.
    Megally, A.
    Colice, G.
    Brightling, C. E.
    AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 2021, 203 (09)
  • [2] Liberty Asthma QUEST: Phase 3 Randomized, Double-Blind, Placebo-Controlled, Parallel-Group Study to Evaluate Dupilumab Efficacy/Safety in Patients with Uncontrolled, Moderate-to-Severe Asthma
    Busse, William W.
    Maspero, Jorge F.
    Rabe, Klaus F.
    Papi, Alberto
    Wenzel, Sally E.
    Ford, Linda B.
    Pavord, Ian D.
    Zhang, Bingzhi
    Staudinger, Heribert
    Pirozzi, Gianluca
    Amin, Nikhil
    Akinlade, Bolanle
    Eckert, Laurent
    Chao, Jingdong
    Graham, Neil M. H.
    Teper, Ariel
    ADVANCES IN THERAPY, 2018, 35 (05) : 737 - 748
  • [3] Liberty Asthma QUEST: Phase 3 Randomized, Double-Blind, Placebo-Controlled, Parallel-Group Study to Evaluate Dupilumab Efficacy/Safety in Patients with Uncontrolled, Moderate-to-Severe Asthma
    William W. Busse
    Jorge F. Maspero
    Klaus F. Rabe
    Alberto Papi
    Sally E. Wenzel
    Linda B. Ford
    Ian D. Pavord
    Bingzhi Zhang
    Heribert Staudinger
    Gianluca Pirozzi
    Nikhil Amin
    Bolanle Akinlade
    Laurent Eckert
    Jingdong Chao
    Neil M. H. Graham
    Ariel Teper
    Advances in Therapy, 2018, 35 : 737 - 748
  • [4] The efficacy and safety of dupilumab in Chinese patients with moderate-to-severe atopic dermatitis: a randomized, double-blind, placebo-controlled study
    Zhao, Y.
    Wu, L.
    Lu, Q.
    Gao, X.
    Zhu, X.
    Yao, X.
    Li, L.
    Li, W.
    Ding, Y.
    Song, Z.
    Liu, L.
    Dang, N.
    Zhang, C.
    Liu, X.
    Gu, J.
    Wang, J.
    Geng, S.
    Liu, Q.
    Guo, Y.
    Dong, L.
    Su, H.
    Bai, L.
    O'Malley, J. T.
    Luo, J.
    Laws, E.
    Mannent, L.
    Ruddy, M.
    Amin, N.
    Bansal, A.
    Ota, T.
    Wang, M.
    Zhang, J.
    BRITISH JOURNAL OF DERMATOLOGY, 2022, 186 (04) : 633 - 641
  • [5] Effects of Dupilumab on Mucus Plugging and Ventilation Defects in Patients with Moderate-to-Severe Asthma: A Randomized, Double-Blind, Placebo-Controlled Trial
    Svenningsen, Sarah
    Kjarsgaard, Melanie
    Haider, Ehsan
    Venegas, Carmen
    Konyer, Norman
    Friedlander, Yonni
    Nasir, Neha
    Boylan, Colm
    Kirby, Miranda
    Nair, Parameswaran
    AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 2023, 208 (09) : 995 - 997
  • [6] Dupilumab Monotherapy in Adults with Moderate-to-Severe Atopic Dermatitis: A 12-Week, Randomized, Double-Blind, Placebo-Controlled Study
    Bieber, Thomas R. M.
    Thaci, Diamant
    Graham, Neil
    Pirozzi, Gianluca
    Teper, Ariel
    Ren, Haobo
    Radin, Allen
    JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 2014, 133 (02) : AB404 - AB404
  • [7] Risankizumab in Patients with Moderate-to-Severe Atopic Dermatitis: A Phase 2, Randomized, Double-Blind, Placebo-Controlled Study
    Stephen K. Tyring
    Phoebe Rich
    Yayoi Tada
    Stefan Beeck
    Izabella Messina
    Jie Liu
    Xiaohong Huang
    Stephen Shumack
    Dermatology and Therapy, 2023, 13 : 595 - 608
  • [8] Risankizumab in Patients with Moderate-to-Severe Atopic Dermatitis: A Phase 2, Randomized, Double-Blind, Placebo-Controlled Study
    Tyring, Stephen K. K.
    Rich, Phoebe
    Tada, Yayoi
    Beeck, Stefan
    Messina, Izabella
    Liu, Jie
    Huang, Xiaohong
    Shumack, Stephen
    DERMATOLOGY AND THERAPY, 2023, 13 (02) : 595 - 608
  • [9] Randomised, double-blind, placebo-controlled study to assess long-term effect of dupilumab on prevention of lung function decline (LFD) in patients with uncontrolled moderate-to-severe asthma: ATLAS trial
    Gomez, L. De Prado
    Pavord, I.
    Busse, W.
    Brightling, C. E.
    Wechsler, M. E.
    Rabe, K. F.
    Zhang, M.
    Xing, J.
    Jacob-Nara, J. A.
    Rowe, P. J.
    EUROPEAN RESPIRATORY JOURNAL, 2022, 60
  • [10] Effect of memantine combination therapy on symptoms in patients with moderate-to-severe depressive disorder: randomized, double-blind, placebo-controlled study
    Amidfar, M.
    Khiabany, M.
    Kohi, A.
    Salardini, E.
    Arbabi, M.
    Azizi, M. Roohi
    Zarrindast, M. -R.
    Mohammadinejad, P.
    Zeinoddini, A.
    Akhondzadeh, S.
    JOURNAL OF CLINICAL PHARMACY AND THERAPEUTICS, 2017, 42 (01) : 44 - 50
12345