Emergence of SARS-COV-2 Spike Protein Escape Mutation Q493R after Treatment for COVID-19

被引：57
|
作者：
Focosi, Daniele [1 ]
Novazzi, Federica [2 ]
Genoni, Angelo [3 ]
Dentali, Francesco [2 ,3 ]
Gasperina, Daniela Dalla [2 ,3 ]
Baj, Andreina [2 ,3 ]
Maggi, Fabrizio [2 ,3 ]
机构：
[1] Pisa Univ Hosp, Pisa, Italy
[2] Azienda Sociosanitaria Terr, Varese, Italy
[3] Univ Insubria, Via Dunant 5, I-21100 Varese, Italy
来源：
EMERGING INFECTIOUS DISEASES | 2021年 / 27卷 / 10期
关键词：
D O I：
10.3201/eid2710.211538
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
We report in vivo selection of a severe acute respiratory syndrome coronavirus 2 spike mutation (Q493R) conferring simultaneous resistance to bamlanivimab and etesivimab. This mutation was isolated from a patient who had coronavirus disease and was treated with these drugs.
引用
收藏
页码：2728 / 2731
页数：4
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