Age-related changes of dietary intake and blood eicosapentaenoic acid, docosahexaenoic acid, and arachidonic acid levels in Japanese men and women

被引:42
|
作者
Kawabata, Terue [1 ]
Hirota, Satoko [1 ]
Hirayama, Tomoko [1 ]
Adachi, Naoko [1 ]
Hagiwara, Chie [1 ]
Iwama, Noriko [1 ]
Kamachi, Keiko [1 ]
Araki, Eiji [1 ]
Kawashima, Hiroshi [2 ]
Kiso, Yoshinobu [2 ]
机构
[1] Kagawa Nutr Univ, Sakado, Saitama 3500288, Japan
[2] Suntory Wellness Ltd, Inst Hlth Care Sci, Osaka 6188503, Japan
关键词
Long-chain polyunsaturated fatty acids; Arachidonic acid; Dietary intake; Erythrocyte membrane; Japanese men and women; POLYUNSATURATED FATTY-ACIDS; FISH-OIL SUPPLEMENTATION; HUMAN HEALTH; N-3; PLASMA; SERUM; INCREASES; BIOMARKER; DISEASE; TISSUE;
D O I
10.1016/j.plefa.2011.01.001
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
We studied the relationship between dietary intake and the blood compositions of eicosapentaenoic acid (EPA), docosahexaenoic acid (DHA), and arachidonic acid (ARA) in four study groups with different ages and sexes. One hundred and four subjects were recruited. Dietary records together with photographic records from 28 consecutive days were amassed and the fatty acid composition in erythrocyte membranes and plasma lipid fractions was analyzed. Fish intake in the elderly group was significantly higher than that in the young group in both men and women. The compositions of ARA in erythrocytes and plasma phospholipids in the elderly were lower than those in the young, but the ARA intake was nearly identical. In the elderly group, the percentage of dietary ARA consumed at the same time as EPA and DHA derived from fish was high. We considered that these fatty acids markedly inhibited the incorporation of dietary ARA into blood phospholipids. (C) 2011 Elsevier Ltd. All rights reserved.
引用
收藏
页码:131 / 137
页数:7
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