Tandem Mass Spectrometry for the Analysis of Ginsenosides in a Phytoadaptogene Composition with Antitumor Properties

被引:1
|
作者
Kazeev, I., V [1 ]
Bocharova, O. A. [1 ]
Shevchenko, V. E. [1 ]
Karpova, R., V [1 ]
Bocharov, E., V [1 ]
Sheichenko, O. P. [2 ]
Kucheryanu, V. G. [3 ]
Baryshnikova, M. A. [1 ]
Matveev, V. B. [1 ]
机构
[1] Minist Hlth Russian Federat, Blokhin Natl Med Res Ctr Oncol, Moscow 115478, Russia
[2] All Russian Sci Res Inst Med & Aromat Plants, Moscow 117216, Russia
[3] Sci Res Inst Gen Pathol & Pathophysiol, Moscow 125315, Russia
关键词
ginseng; ginsenosides; HPLC-MS; MS; phytoadaptogene; antitumor activity; PANAX-GINSENG; CANCER; CELLS; RD;
D O I
10.1134/S0040579521050225
中图分类号
TQ [化学工业];
学科分类号
0817 ;
摘要
The results of an analysis for ginsenosides in the Multiphytoadaptogene (MPA) phytoadaptogene composition with antitumor properties by high-performance liquid chromatography with tandem mass spectrometry (HPLC-MS/MS) are presented. Ginsenosides are identified with the use of commercial standards of ginsenosides and some literature data. Ginsenosides Rb-1, Rb-2, Rc, Rd, Rg(1), Rg(2), Re, Rf, and Ro are revealed in MPA. The results could be used for the standardization and quality control of phytocomplexes containing triterpenoid glycosides.
引用
收藏
页码:1246 / 1257
页数:12
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