Simultaneous determination of ginsenosides by high-performance liquid chromatography with tandem mass spectrometry detection

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[1] Rodin, I.A.
[2] Stavrianidi, A.N.
[3] Braun, A.V.
[4] Shpigun, O.A.
[5] Berizovskaya, E.I.
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Stavrianidi, A.N. | 1600年 / Maik Nauka Publishing / Springer SBM卷 / 69期
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An approach to the simultaneous registration of ginsenosides in herbal extracts and commercial products was developed on the basis of liquid chromatography/mass spectrometry. The approach was validated for four major ginsenosides: Rg1; Rb1; Rf; and Re determined in extracts from roots of Panax ginseng; a phyto-formulation and a tea produced from the roots. The limits of detection for two applied detection modes belong to the range 0.001–0.01 μg/mL. Samples were analyzed by reversed-phase chromatography with a C18 adsorbent. Electrospray ionization in the positive ion mode and a hybrid linear-trap tandem mass spectrometry detection system were used to monitor compounds. © 2014; Pleiades Publishing; Ltd;
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