Tandem Mass Spectrometry for the Analysis of Ginsenosides in a Phytoadaptogene Composition with Antitumor Properties

被引:1
|
作者
Kazeev, I., V [1 ]
Bocharova, O. A. [1 ]
Shevchenko, V. E. [1 ]
Karpova, R., V [1 ]
Bocharov, E., V [1 ]
Sheichenko, O. P. [2 ]
Kucheryanu, V. G. [3 ]
Baryshnikova, M. A. [1 ]
Matveev, V. B. [1 ]
机构
[1] Minist Hlth Russian Federat, Blokhin Natl Med Res Ctr Oncol, Moscow 115478, Russia
[2] All Russian Sci Res Inst Med & Aromat Plants, Moscow 117216, Russia
[3] Sci Res Inst Gen Pathol & Pathophysiol, Moscow 125315, Russia
关键词
ginseng; ginsenosides; HPLC-MS; MS; phytoadaptogene; antitumor activity; PANAX-GINSENG; CANCER; CELLS; RD;
D O I
10.1134/S0040579521050225
中图分类号
TQ [化学工业];
学科分类号
0817 ;
摘要
The results of an analysis for ginsenosides in the Multiphytoadaptogene (MPA) phytoadaptogene composition with antitumor properties by high-performance liquid chromatography with tandem mass spectrometry (HPLC-MS/MS) are presented. Ginsenosides are identified with the use of commercial standards of ginsenosides and some literature data. Ginsenosides Rb-1, Rb-2, Rc, Rd, Rg(1), Rg(2), Re, Rf, and Ro are revealed in MPA. The results could be used for the standardization and quality control of phytocomplexes containing triterpenoid glycosides.
引用
收藏
页码:1246 / 1257
页数:12
相关论文
共 50 条
  • [41] Multimodal Tandem Mass Spectrometry Techniques for the Analysis of Phosphopeptides
    Paris, Johanna
    Theisen, Alina
    Marzullo, Bryan P.
    Haris, Anisha
    Morgan, Tomos E.
    Barrow, Mark P.
    O'Hara, John
    O'Connor, Peter B.
    JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY, 2022, : 1126 - 1133
  • [42] Analysis of isoaspartate in peptides by electrospray tandem mass spectrometry
    Lehmann, WD
    Schlosser, A
    Erben, G
    Pipkorn, R
    Bossemeyer, D
    Kinzel, V
    PROTEIN SCIENCE, 2000, 9 (11) : 2260 - 2268
  • [43] Sirolimus analysis in blood by tandem mass spectrometry.
    Kumar, A
    CLINICAL IMMUNOLOGY, 2002, 103 (03) : S85 - S85
  • [44] Versatility of tandem mass spectrometry for focused analysis of oxylipids
    Petta, Tania
    Moraes, Luiz A. B.
    Faccioli, Lucia H.
    JOURNAL OF MASS SPECTROMETRY, 2015, 50 (07): : 879 - 890
  • [45] Recent developments in tandem mass spectrometry for lipidomic analysis
    Zehethofer, Nicole
    Pinto, Deuanand M.
    ANALYTICA CHIMICA ACTA, 2008, 627 (01) : 62 - 70
  • [46] ANALYSIS OF TESTOSTERONE ESTERS BY TANDEM MASS-SPECTROMETRY
    CAIRNS, T
    SIEGMUND, EG
    RADER, B
    JOURNAL OF AOAC INTERNATIONAL, 1993, 76 (02) : 306 - 312
  • [47] Phosphorothioate RNA Analysis by NETD Tandem Mass Spectrometry
    Peters-Clarke, Trenton M.
    Quan, Qiuwen
    Anderson, Benton J.
    McGee, William M.
    Lohr, Emily
    Hebert, Alexander S.
    Westphall, Michael S.
    Coon, Joshua J.
    MOLECULAR & CELLULAR PROTEOMICS, 2024, 23 (04)
  • [48] Direct Analysis of Protein Mixtures by Tandem Mass Spectrometry
    John R. Yates
    Ashley L. McCormack
    David Schieltz
    Edwin Carmack
    Andrew Link
    Journal of Protein Chemistry, 1997, 16 (5): : 495 - 497
  • [49] TANDEM MASS-SPECTROMETRY IN TRACE TOXICANT ANALYSIS
    MCLAFFERTY, FW
    BIOMEDICAL MASS SPECTROMETRY, 1981, 8 (09): : 446 - 448
  • [50] Rapid analysis of Eleutheroside by electrospray tandem mass spectrometry
    Guo, MQ
    Song, FR
    Liu, ZQ
    Liu, SY
    CHINESE JOURNAL OF ANALYTICAL CHEMISTRY, 2003, 31 (04) : 476 - 480