HEPATITIS After HCV cure, HBV cure?

被引:3
|
作者
Lucifora, Julie [1 ]
Trepo, Christian [1 ]
机构
[1] Canc Res Ctr Lyon, CNRS UMR 5286, INSERM U1052, F-69424 Lyon 03, France
关键词
B-VIRUS; APOPTOSIS; CLEARANCE; INHIBITOR;
D O I
10.1038/nrgastro.2015.103
中图分类号
R57 [消化系及腹部疾病];
学科分类号
摘要
Current treatments efficiently control chronic HBV infection but they do not lead to its elimination. Now, Ebert and colleagues have shown that cellular inhibitor of apoptosis proteins (cIAPs) prevent TNF-mediated killing of infected hepatocytes and that cIAP antagonists might lead to HBV cure by promoting death of infected cells.
引用
收藏
页码:377 / 378
页数:2
相关论文
共 50 条
  • [31] Hepatocellular Carcinoma Risk After Hepatitis C Cure
    Oloruntoba, Omobonike O.
    Muir, Andrew J.
    CURRENT TREATMENT OPTIONS IN INFECTIOUS DISEASES, 2018, 10 (02) : 330 - 336
  • [32] Hepatocellular Carcinoma Risk After Hepatitis C Cure
    Omobonike O. Oloruntoba
    Andrew J. Muir
    Current Treatment Options in Infectious Diseases, 2018, 10 (2) : 330 - 336
  • [33] Pathway to global elimination of hepatitis B: HBV cure is just the first step
    Howell, Jessica
    Seaman, Chris
    Wallace, Jack
    Xiao, Yinzong
    Scott, Nick
    Davies, Jane
    de Santis, Teresa
    Adda, Danjuma
    El-Sayed, Manal
    Feld, Jordan J.
    Gane, Edward
    Lacombe, Karine
    Lesi, Olufunmilayo
    Mohamed, Rosmawati
    Silva, Marcelo
    Tu, Thomas
    Revill, Peter
    Hellard, Margaret E.
    HEPATOLOGY, 2023, 78 (03) : 976 - 990
  • [34] Targeting the multifunctional HBV core protein as a potential cure for chronic hepatitis B
    Viswanathan, Usha
    Mani, Nagraj
    Hu, Zhanying
    Ban, Haiqun
    Du, Yanming
    Hu, Jin
    Chang, Jinhong
    Guo, Ju-Tao
    ANTIVIRAL RESEARCH, 2020, 182
  • [35] HBV cure: need for concerted efforts
    Kalkeri, Raj
    FUTURE VIROLOGY, 2016, 11 (02) : 105 - 108
  • [36] Aiming for cure in HBV and HDV infection
    Petersen, Joerg
    Thompson, Alexander J.
    Levrero, Massimo
    JOURNAL OF HEPATOLOGY, 2016, 65 (04) : 835 - 848
  • [37] High HCV Cure Rates After Directly Acting Antivirals In Patients with Chronic Hepatitis C and Psychiatric Disorders
    Moore, Anne
    Hepner, Ashley
    Abdulameer, Ahmed
    Leff, Phillip
    Reynolds, Justin
    Arendt, Karen
    Gish, Robert
    Manch, Richard
    Kohli, Anita
    HEPATOLOGY, 2016, 64 : 812A - 812A
  • [38] Aiming at the cccDNA for a cure of HBV persistence
    Zhang, Huatang
    CHINESE SCIENCE BULLETIN-CHINESE, 2019, 64 (30): : 3059 - 3060
  • [39] Hepatitis B cure: modeling the economics of a potential cost of a cure
    Toy, Mehlika
    So, Samuel
    Hutton, David W.
    CURRENT OPINION IN HIV AND AIDS, 2020, 15 (03) : 208 - 212
  • [40] Global scientific strategy for an HBV cure
    Revill, P.
    Zoulim, F.
    Penicaud, C.
    JOURNAL OF VIRAL HEPATITIS, 2018, 25 : 43 - 43