Current treatments efficiently control chronic HBV infection but they do not lead to its elimination. Now, Ebert and colleagues have shown that cellular inhibitor of apoptosis proteins (cIAPs) prevent TNF-mediated killing of infected hepatocytes and that cIAP antagonists might lead to HBV cure by promoting death of infected cells.
机构:
Thomas Jefferson Univ Hosp, Dept Med, Div Gastroenterol & Hepatol, Philadelphia, PA 19107 USAThomas Jefferson Univ Hosp, Dept Med, Div Gastroenterol & Hepatol, Philadelphia, PA 19107 USA
Hamidu, Rukaiya Bashir
Hann, Richard R.
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机构:
Thomas Jefferson Univ Hosp, Liver Dis prevent Ctr, Div Gastroenterol & Hepatol, Philadelphia, PA 19107 USAThomas Jefferson Univ Hosp, Dept Med, Div Gastroenterol & Hepatol, Philadelphia, PA 19107 USA