Synthesis and conformational analysis of novel tertiary amides derived from N-[(S)-α-phenylethyl]-1,3-Imidazolidine

被引：2
|
作者：
Santacruz-Juarez, Ericka [1 ,2 ]
Hopfl, Herbert [3 ]
Huelgas, Gabriela [1 ]
Romero, Oscar [2 ]
Castro, Alejandro [2 ]
Anaya de Parrodi, Cecilia [1 ]
Morales-Meza, Sharity [4 ]
Sanchez, Mario [4 ]
机构：
[1] Univ Amer Puebla, Dept Quim & Biol, Santa Catarina 72820, Cholula, Mexico
[2] Univ Politecn Tlaxcala, Av Univ Politecn Tlaxcala 1, Municipio De Tepeyanco 90180, Tlaxcala, Mexico
[3] Univ Autonoma Estado Morelos, Inst Ciencias Basicas & Aplicadas, Ctr Invest Quim, Av Univ 1001, Cuernavaca 62209, Morelos, Mexico
[4] Ctr Invest Mat Avanzados SC, Alianza Norte 202,P2T, Apodaca 66628, NL, Mexico
来源：
ARKIVOC | 2017年
关键词：
Tertiary amides; variable temperature RMN; theoretical analysis; Z- and E-rotamer; BOND FORMATION; AMINES; ALCOHOLS; TRANSAMIDATION; ALDEHYDES; NICKEL; GOLD; C-2;
D O I：
10.3998/ark.5550190.p010.022
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
The synthesis of three chiral tertiary amides by ring opening of the symmetric 1,3-imidazolidine 2 under mild conditions is described. H-1 NMR dynamics studies were performed to identify three rotamers present in solution, which were also examined by DFT calculations.
引用
收藏
页码：89 / 99
页数：11
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