Synthesis and photophysical properties of novel succinimidyl benzazole derivatives, evaluated by Candida albicans ATCC 10231 fluorescent staining

被引：30
|
作者：
dos Santos, Rosane Catarina [1 ]
da Silva Faleiro, Nalva Vivian [1 ]
Campo, Leandra Franciscato [1 ]
Scroferneker, Maria Lucia [2 ]
Corbellini, Valeriano Antonio
Rodembusch, Fabiano Severo [1 ]
Stefani, Valter [1 ]
机构：
[1] Univ Fed Rio Grande do Sul, Inst Quim, BR-91501970 Porto Alegre, RS, Brazil
[2] Univ Fed Rio Grande do Sul, Inst Ciencias Basicas Saude, BR-90050170 Porto Alegre, RS, Brazil
来源：
TETRAHEDRON LETTERS | 2011年 / 52卷 / 23期
关键词：
Fluorescent probes; ESIPT; Succinimidyl dyes; Epifluorescence; Candida albicans; INTRAMOLECULAR PROTON-TRANSFER; CLINICAL SPECIMENS; FUNGAL ELEMENTS; IN-VIVO; VISUALIZATION; INFECTIONS; CALCOFLUOR; CELLS; YEAST;
D O I：
10.1016/j.tetlet.2011.04.026
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
New fluorescent succinimidyl benzazole derivatives were synthesised and successfully used to stain Candida albicans ATCC 10231 cells. The dyes were characterised by means of infrared, C-13 and H-1 NMR spectroscopies and elemental analysis. UV-Vis and steady-state fluorescence in solution were also applied to characterise their photophysical behaviour. The novel dyes were fluorescent in the yellow-green region by a phototautomerism in the excited state (ESIPT) with a large Stokes shift (9065-10962 cm(-1)). Dual fluorescence could also be observed depending on the solvent polarity. The present dyes were used as new probes by means of culture methodology or direct staining to study the micromorphology of Candida albicans. (C) 2011 Elsevier Ltd. All rights reserved.
引用
收藏
页码：3048 / 3053
页数：6
相关论文
共 50 条
  • [31] Synthesis and photophysical properties of novel thiophenylacrylonitrile derivatives containing a triphenylamine moiety
    Fang, Haiyan
    Yu, Mingxin
    JOURNAL OF CHEMICAL RESEARCH, 2009, (12) : 729 - 731
  • [32] Synthesis, characterization and photophysical properties of novel thiazole substituted pyridine derivatives
    Suryawanshi, Manjusha
    Gujar, Varsha
    Ottoor, Divya
    Bobade, Vivek
    INDIAN JOURNAL OF CHEMISTRY SECTION B-ORGANIC CHEMISTRY INCLUDING MEDICINAL CHEMISTRY, 2019, 58 (12): : 1361 - 1374
  • [33] Synthesis, characterization and photophysical properties of novel tetrasubstituted phthalocyaninato zinc derivatives
    Liu, Qing-He
    Fu, Qiang
    Yang, Jin
    Ma, Ji-Cheng
    Li, Wei-Li
    Wang, Xue
    JOURNAL OF MOLECULAR STRUCTURE, 2010, 963 (01) : 41 - 44
  • [34] Synthesis, oxidation and photophysical properties of novel derivatives of acyclic aromatic amines
    Kosa, Csaba
    Mosnacek, Jaroslav
    Bilesova, Adela
    Kasak, Peter
    Kronek, Juraj
    Danko, Martin
    Kollar, Jozef
    COLLECTION OF CZECHOSLOVAK CHEMICAL COMMUNICATIONS, 2007, 72 (09) : 1255 - 1268
  • [35] Microwave synthesis, photophysical properties of novel fluorescent iminocoumarins and their application in textile printing
    Elgemeie, G. H.
    Ahmed, K. A.
    Ahmed, E. A.
    Helal, M. H.
    Masoud, D. M.
    PIGMENT & RESIN TECHNOLOGY, 2015, 44 (02) : 87 - 93
  • [36] Synthesis and Characterization of a Novel Intrinsically Fluorescent Analog of Cholesterol with Improved Photophysical Properties
    Lehmann, Max
    Halder, Senjuti
    Reinholdt, Peter
    Bashawat, Mohammad
    Scheidt, Holger A.
    Leopold, Jenny
    Schiller, Jurgen
    di Prima, Duccio
    Akkerman, Vibeke
    Szomek, Maria
    Lauritsen, Line
    Kongsted, Jacob
    Mueller, Peter
    Wessig, Pablo
    Wuestner, Daniel
    ANALYTICAL CHEMISTRY, 2024, 96 (47) : 18596 - 18604
  • [37] Synthesis and spectral properties of novel fluorescent diethoxycarbonyl glycoluril derivatives
    She, Nengfang
    Gao, Meng
    Cao, Liping
    Yin, Guodong
    Wu, Anxin
    SYNLETT, 2007, (16) : 2533 - 2536
  • [38] Synthesis of Novel Spiro-Oxazino-Quinoline Derivatives and Study of Their Photophysical Properties
    Bhupendra S. Rane
    Muddassar A. Kazi
    Sandeep M. Bagul
    Deepak P. Shelar
    Raghunath B. Toche
    Madhukar N. Jachak
    Journal of Fluorescence, 2010, 20 : 415 - 420
  • [39] Synthesis and photophysical properties of two novel 2-naphthyl ketone derivatives
    Deng, Yunlong
    Feng, Shasha
    Cao, Duxia
    Liu, Zhiqiang
    Huagong Xuebao/CIESC Journal, 2010, 61 (04): : 1052 - 1057
  • [40] Synthesis of Novel Spiro-Oxazino-Quinoline Derivatives and Study of Their Photophysical Properties
    Rane, Bhupendra S.
    Kazi, Muddassar A.
    Bagul, Sandeep M.
    Shelar, Deepak P.
    Toche, Raghunath B.
    Jachak, Madhukar N.
    JOURNAL OF FLUORESCENCE, 2010, 20 (01) : 415 - 420
12345