Structural features of the legume lectins

被引:20
|
作者
Hamelryck, TW [1 ]
Loris, R [1 ]
Bouckaert, J [1 ]
Wyns, L [1 ]
机构
[1] Free Univ Brussels VIB, Lab Ultrastruct, B-1640 Rhode St Genese, Belgium
关键词
lectin-like proteins; legume lectins; protein-sugar interactions; quaternary structure; x-ray crystallography;
D O I
10.4052/tigg.10.349
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
The legume lectins are a family of carbohydrate binding proteins found in the Leguminosae plants and are used as a model system for studying protein-carbohydrate interactions. The different legume lectins show a remarkable range of sugar specificities, despite the high sequential and structural similarity of their subunits. Moreover, their subunits can associate into a number of different multimers. The unique variability of quaternary structure has implications for the formation of cross-linked lattices and binding of hydrophobic ligands.
引用
收藏
页码:349 / 360
页数:12
相关论文
共 50 条
  • [41] Structural Prediction and Characterization of Canavalia grandiflora (ConGF) Lectin Complexed with MMP1: Unveiling the Antiglioma Potential of Legume Lectins
    Leal, Rodrigo Bainy
    Mann, Josiane
    Pinto-Junior, Vanir Reis
    Oliveira, Messias Vital
    Silva Osterne, Vinicius Jose
    Victoria Wolin, Ingrid Alessandra
    Machado Nascimento, Ana Paula
    Welter, Priscilla Gomes
    Sousa Ferreira, Valeria Maria
    Silva, Alice Araujo
    Seeger, Rodrigo Lopes
    Nascimento, Kyria Santiago
    Cavada, Benildo Sousa
    MOLECULES, 2022, 27 (20):
  • [42] Interplay between metal binding and cis/trans isomerization in legume lectins:: Structural and thermodynamic study of P-angolensis lectin
    Garcia-Pino, Abel
    Buts, Lieven
    Wyns, Lode
    Loris, Remy
    JOURNAL OF MOLECULAR BIOLOGY, 2006, 361 (01) : 153 - 167
  • [43] Crystallization of two related lectins from the legume plant Dolichos biflorus
    Dao-Thi, MH
    Hamelryck, TW
    Bouckaert, J
    Korber, F
    Burkow, V
    Poortmans, F
    Etzler, M
    Strecker, G
    Wyns, L
    Loris, R
    ACTA CRYSTALLOGRAPHICA SECTION D-STRUCTURAL BIOLOGY, 1998, 54 : 1446 - 1449
  • [44] How proteins bind carbohydrates: Lessons from legume lectins.
    Sharon, N
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2000, 219 : U46 - U46
  • [45] Recent advances in the use of legume lectins for the diagnosis and treatment of breast cancer
    Cavada, Benildo Sousa
    Oliveira, Messias Vital
    Osterne, Vinicius Jose Silva
    Pinto-Junior, Vanir Reis
    Martins, Francisco William Viana
    Correia-Neto, Cornevile
    Pinheiro, Ronald Feitosa
    Leal, Rodrigo Bainy
    Nascimento, Kyria Santiago
    BIOCHIMIE, 2023, 208 : 100 - 116
  • [46] LEGUME LECTINS INTERACT WITH MURAMIC ACID AND N-ACETYLMURAMIC ACID
    AYOUBA, A
    CHATELAIN, C
    ROUGE, P
    FEBS LETTERS, 1991, 289 (01) : 102 - 104
  • [47] Carbohydrate recognition by legume lectins and the endoplasmic reticulum chaperones calreticulin and calnexin
    Surolia, A
    GLYCOBIOLOGY, 2002, 12 (10) : 686 - 686
  • [48] CIRCULAR PERMUTATION OF AMINO-ACID-SEQUENCES AMONG LEGUME LECTINS
    HEMPERLY, JJ
    CUNNINGHAM, BA
    TRENDS IN BIOCHEMICAL SCIENCES, 1983, 8 (03) : 100 - 102
  • [49] Hydrocarbon-Binding Peptides from Legume Lectins in Relation to Different Host Specificity upon Legume–Rhizobium Symbiosis
    Al. Kh. Baiymiev
    A. V. Chemeris
    An. Kh. Baiymiev
    V. A. Vakhitov
    Russian Journal of Genetics, 2001, 37 : 156 - 161
  • [50] ROLE OF LECTINS AND LIPOPOLYSACCHARIDES IN THE RECOGNITION PROCESS OF SPECIFIC LEGUME-RHIZOBIUM SYMBIOSIS
    KATO, G
    MARUYAMA, Y
    NAKAMURA, M
    AGRICULTURAL AND BIOLOGICAL CHEMISTRY, 1979, 43 (05): : 1085 - 1092