Structural features of the legume lectins

被引:20
|
作者
Hamelryck, TW [1 ]
Loris, R [1 ]
Bouckaert, J [1 ]
Wyns, L [1 ]
机构
[1] Free Univ Brussels VIB, Lab Ultrastruct, B-1640 Rhode St Genese, Belgium
关键词
lectin-like proteins; legume lectins; protein-sugar interactions; quaternary structure; x-ray crystallography;
D O I
10.4052/tigg.10.349
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
The legume lectins are a family of carbohydrate binding proteins found in the Leguminosae plants and are used as a model system for studying protein-carbohydrate interactions. The different legume lectins show a remarkable range of sugar specificities, despite the high sequential and structural similarity of their subunits. Moreover, their subunits can associate into a number of different multimers. The unique variability of quaternary structure has implications for the formation of cross-linked lattices and binding of hydrophobic ligands.
引用
收藏
页码:349 / 360
页数:12
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