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Structural features of the legume lectins
被引:20
|作者:
Hamelryck, TW
[1
]
Loris, R
[1
]
Bouckaert, J
[1
]
Wyns, L
[1
]
机构:
[1] Free Univ Brussels VIB, Lab Ultrastruct, B-1640 Rhode St Genese, Belgium
关键词:
lectin-like proteins;
legume lectins;
protein-sugar interactions;
quaternary structure;
x-ray crystallography;
D O I:
10.4052/tigg.10.349
中图分类号:
Q5 [生物化学];
Q7 [分子生物学];
学科分类号:
071010 ;
081704 ;
摘要:
The legume lectins are a family of carbohydrate binding proteins found in the Leguminosae plants and are used as a model system for studying protein-carbohydrate interactions. The different legume lectins show a remarkable range of sugar specificities, despite the high sequential and structural similarity of their subunits. Moreover, their subunits can associate into a number of different multimers. The unique variability of quaternary structure has implications for the formation of cross-linked lattices and binding of hydrophobic ligands.
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页码:349 / 360
页数:12
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