Background: The emotion of disgust has been linked with the underlying nature of the contamination subtype of obsessive-compulsive disorder (C-OCD). Prior studies show that disgust contributes to the development of C-OCD by reinforcing avoidance strategies. Therefore, experiential avoidance (EA) may influence the effect between disgust sensitivity (DS) and C-OCD symptom severity. This study aimed to investigate the mediational role of EA between DS and C-OCD severity. Methods: A cross-sectional design was adopted with 45 patients of OCD and 45 healthy controls. Both the groups were assessed on the Obsessive-Compulsive Inventory, the Disgust Scale (Revised), and Acceptance and Action Questionnaire-II. Yale-Brown Obsessive Compulsive Scale (Y-BOCS) checklist and symptom severity scale were additionally administered to the patients with OCD. Independent t-tests, Pearson's product-moment correlation, regression analysis, and mediation analysis were used. Results: DS and EA were positively associated with contamination-washing symptoms and symptom severity. Regression analysis indicated that DS and EA were highly associated with contamination/washing severity scores among both the patients with C-OCD and the healthy controls. Conclusion: The study implicates that disgust is a central emotion underlying the presentation of obsessions and compulsions, which are of contamination concerns. Further, EA has a role in the maintenance of OCD through avoidance learning; however, it may not be interacting with DS to cause OCD.
机构:
Medical Research Council Unit on Anxiety Disorders, University of Stellenbosch, Cape TownMedical Research Council Unit on Anxiety Disorders, University of Stellenbosch, Cape Town
Stein D.J.
Liu Y.
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Medical Research Council Unit on Anxiety Disorders, University of Stellenbosch, Cape TownMedical Research Council Unit on Anxiety Disorders, University of Stellenbosch, Cape Town
Liu Y.
Shapira N.A.
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Medical Research Council Unit on Anxiety Disorders, University of Stellenbosch, Cape TownMedical Research Council Unit on Anxiety Disorders, University of Stellenbosch, Cape Town
Shapira N.A.
Goodman W.K.
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Medical Research Council Unit on Anxiety Disorders, University of Stellenbosch, Cape TownMedical Research Council Unit on Anxiety Disorders, University of Stellenbosch, Cape Town
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UMC Utrecht, Rudolf Magnus Inst Neurosci, Dept Psychiat, NL-3508 GA Utrecht, NetherlandsUMC Utrecht, Rudolf Magnus Inst Neurosci, Dept Psychiat, NL-3508 GA Utrecht, Netherlands
Vulink, NCC
Denys, D
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UMC Utrecht, Rudolf Magnus Inst Neurosci, Dept Psychiat, NL-3508 GA Utrecht, NetherlandsUMC Utrecht, Rudolf Magnus Inst Neurosci, Dept Psychiat, NL-3508 GA Utrecht, Netherlands
Denys, D
Bus, L
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UMC Utrecht, Rudolf Magnus Inst Neurosci, Dept Psychiat, NL-3508 GA Utrecht, NetherlandsUMC Utrecht, Rudolf Magnus Inst Neurosci, Dept Psychiat, NL-3508 GA Utrecht, Netherlands
Bus, L
Westenberg, HGM
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UMC Utrecht, Rudolf Magnus Inst Neurosci, Dept Psychiat, NL-3508 GA Utrecht, NetherlandsUMC Utrecht, Rudolf Magnus Inst Neurosci, Dept Psychiat, NL-3508 GA Utrecht, Netherlands