Comorbidity of obsessive-compulsive disorder with obsessive-compulsive personality disorder: Does it imply a specific subtype of obsessive-compulsive disorder?
The present study examined whether the comorbidity of obsessive-compulsive personality disorder (OCPD) and obsessive-compulsive disorder (OCD) constitute a specific subtype of OCD. The study sample consisted of 146 consecutive outpatients with a DSM-IV diagnosis of OCD. Diagnoses were established using MINI, IPDE, YBOCS and YBOCS-SC. OCD patients with comorbid OCPD were compared with OCD patients without OCPD on various sociodemographic and clinical variables. Almost one third of the OCD subjects met criteria for comorbid OCPD. OCD + OCPD patients had a significantly earlier age at onset of initial OC symptoms, earlier age at onset of OCD and more obsessions and compulsions than pure obsessions compared to the patients with OCDOCPD. OCD + OCPD patients also had a higher rate of comorbidity with avoidant personality disorder and showed more impairment in global functioning. There were not differences between the two sub-groups on severity of OCD symptoms and also on type of OCD onset. Our results indicate that the comorbidity of OCD with OCPD is associated with a number of specific clinical characteristics of OCD. These findings in conjunction with of current clinical, family and genetic studies provide some initial evidence that OCD comorbid with OCPD constitute a specific subtype of OCD. (C) 2010 Elsevier Ireland Ltd. All rights reserved.
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Massachusetts Gen Hosp, Child CBT Program, 151 Merrimac St,3rd Floor, Boston, MA 02114 USAMassachusetts Gen Hosp, Child CBT Program, 151 Merrimac St,3rd Floor, Boston, MA 02114 USA
Park, Jennifer M.
Storch, Eric A.
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Univ S Florida, Dept Psychol, Tampa, FL 33620 USA
Univ S Florida, Dept Pediat, Tampa, FL 33620 USA
Univ S Florida, Dept Psychiat & Behav Neurosci, Tampa, FL USAMassachusetts Gen Hosp, Child CBT Program, 151 Merrimac St,3rd Floor, Boston, MA 02114 USA
Storch, Eric A.
Pinto, Anthony
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North Shore LIJ Hlth Syst, Zucker Hillside Hosp, Div Psychiat Res, Glen Oaks, NY USA
Hofstra North Shore LIJ Sch Med, Dept Psychiat, Hempstead, NY USAMassachusetts Gen Hosp, Child CBT Program, 151 Merrimac St,3rd Floor, Boston, MA 02114 USA
Pinto, Anthony
Lewin, Adam B.
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Univ S Florida, Dept Psychol, Tampa, FL 33620 USA
Univ S Florida, Dept Pediat, Tampa, FL 33620 USA
Univ S Florida, Dept Psychiat & Behav Neurosci, Tampa, FL USAMassachusetts Gen Hosp, Child CBT Program, 151 Merrimac St,3rd Floor, Boston, MA 02114 USA
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Univ Hertfordshire, Queen Elizabeth II Hosp, Postgrad Med Sch, Welwyn Garden City AL7 4HQ, Herts, EnglandUniv Hertfordshire, Queen Elizabeth II Hosp, Postgrad Med Sch, Welwyn Garden City AL7 4HQ, Herts, England
Fineberg, Naomi A.
Sharma, Punita
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机构:Univ Hertfordshire, Queen Elizabeth II Hosp, Postgrad Med Sch, Welwyn Garden City AL7 4HQ, Herts, England
Sharma, Punita
Sivakumaran, Thanusha
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机构:Univ Hertfordshire, Queen Elizabeth II Hosp, Postgrad Med Sch, Welwyn Garden City AL7 4HQ, Herts, England
Sivakumaran, Thanusha
Sahakian, Barbara
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机构:Univ Hertfordshire, Queen Elizabeth II Hosp, Postgrad Med Sch, Welwyn Garden City AL7 4HQ, Herts, England
Sahakian, Barbara
Chamberlain, Sam
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机构:Univ Hertfordshire, Queen Elizabeth II Hosp, Postgrad Med Sch, Welwyn Garden City AL7 4HQ, Herts, England
机构:
Columbia Univ, New York State Psychiat Inst, New York, NY 10032 USA
Columbia Univ, Dept Psychiat, New York, NY 10032 USAColumbia Univ, New York State Psychiat Inst, New York, NY 10032 USA
Pinto, Anthony
Steinglass, Joanna E.
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Columbia Univ, New York State Psychiat Inst, New York, NY 10032 USA
Columbia Univ, Dept Psychiat, New York, NY 10032 USAColumbia Univ, New York State Psychiat Inst, New York, NY 10032 USA
Steinglass, Joanna E.
Greene, Ashley L.
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Columbia Univ, New York State Psychiat Inst, New York, NY 10032 USAColumbia Univ, New York State Psychiat Inst, New York, NY 10032 USA
Greene, Ashley L.
Weber, Elke U.
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Columbia Univ, Columbia Business Sch, Ctr Decis Sci, New York, NY 10032 USAColumbia Univ, New York State Psychiat Inst, New York, NY 10032 USA
Weber, Elke U.
Simpson, H. Blair
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Columbia Univ, New York State Psychiat Inst, New York, NY 10032 USA
Columbia Univ, Dept Psychiat, New York, NY 10032 USAColumbia Univ, New York State Psychiat Inst, New York, NY 10032 USA