Evaluation of a Cryptococcal antigen Lateral Flow Assay in serum and cerebrospinal fluid for rapid diagnosis of cryptococcosis in Colombia

被引：1
|
作者：
Caceres, Diego H. [1 ]
Zuluaga, Alejandra [1 ]
Tabares, Angela M. [1 ]
Chiller, Tom [2 ]
Gonzalez, Angel [3 ]
Gomez, Beatriz L. [1 ,4 ]
机构：
[1] CIB, Med & Expt Mycol Grp, Medellin, Colombia
[2] Ctr Dis Control & Prevent, Mycot Dis Branch, Atlanta, GA USA
[3] Univ Antioquia, Escuela Microbiol, Grp Invest Microbiol Basica & Aplicada, Medellin, Colombia
[4] Univ Rosario, Escuela Med & Ciencias Salud, Bogota, Colombia
来源：
REVISTA DO INSTITUTO DE MEDICINA TROPICAL DE SAO PAULO | 2017年 / 59卷
关键词：
Cryptococcosis; Cryptococcus; Antigen; Diagnosis; Point-of-care; Lateral Flow Assay; Immunochromatographic assay; Latex agglutination system; IMMUNOASSAY;
D O I：
10.1590/S1678-9946201759076
中图分类号：
R51 [传染病];
学科分类号：
100401 ;
摘要：
A Lateral Flow Assay to detect cryptococcal antigen (CrAg (R) LFA) in serum and cerebrospinal fluid for the rapid diagnosis of cryptococcosis was evaluated. A retrospective validation was performed. Sensitivity and specificity of the CrAg (R) LFA was 100%. High concordance (kappa index=1.0) between Cryptococcal Antigen Latex Agglutination System (CALAS (R)) and CrAg (R) LFA was observed. CrAg (R) LFA showed higher analytical sensitivity for detecting low concentrations of cryptococcal antigen.
引用
收藏
页数：3
相关论文
共 50 条
  • [41] Clinical performance of the IMMY cryptococcal antigen lateral flow assay in dogs and cats
    Langner, Kathrin F. A.
    Yang, Wen-Jie
    JOURNAL OF VETERINARY INTERNAL MEDICINE, 2022, 36 (06) : 1966 - 1973
  • [42] Clinical Utility of the Cryptococcal Antigen Lateral Flow Assay in a Diagnostic Mycology Laboratory
    McMullan, Brendan J.
    Halliday, Catriona
    Sorrell, Tania C.
    Judd, David
    Sleiman, Sue
    Marriott, Debbie
    Olma, Tom
    Chen, Sharon C. -A.
    PLOS ONE, 2012, 7 (11):
  • [43] MEASUREMENT OF CRYPTOCOCCAL ANTIGEN IN SERUM AND CEREBROSPINAL-FLUID - VALUE IN THE MANAGEMENT OF AIDS-ASSOCIATED CRYPTOCOCCAL MENINGITIS
    POWDERLY, WG
    CLOUD, GA
    DISMUKES, WE
    SAAG, MS
    CLINICAL INFECTIOUS DISEASES, 1994, 18 (05) : 789 - 792
  • [44] Evaluation of a Newly Developed Lateral Flow Immunoassay for the Diagnosis of Cryptococcosis
    Lindsley, Mark D.
    Mekha, Nanthawan
    Baggett, Henry C.
    Surinthong, Yupha
    Autthateinchai, Rinrapas
    Sawatwong, Pongpun
    Harris, Julie R.
    Park, Benjamin J.
    Chiller, Tom
    Balajee, S. Arunmozhi
    Poonwan, Natteewan
    CLINICAL INFECTIOUS DISEASES, 2011, 53 (04) : 321 - 325
  • [45] Rapid diagnosis of tuberculous meningitis by a dot immunobinding assay to detect mycobacterial antigen in cerebrospinal fluid specimens
    Sumi, MG
    Mathai, A
    Sarada, C
    Radhakrishnan, VV
    JOURNAL OF CLINICAL MICROBIOLOGY, 1999, 37 (12) : 3925 - 3927
  • [46] Evaluation of Fingerstick Cryptococcal Antigen Lateral Flow Assay in HIV-Infected Persons: A Diagnostic Accuracy Study
    Williams, Darlisha A.
    Kiiza, Tadeo
    Kwizera, Richard
    Kiggundu, Reuben
    Velamakanni, Sruti
    Meya, David B.
    Rhein, Joshua
    Boulware, David R.
    CLINICAL INFECTIOUS DISEASES, 2015, 61 (03) : 464 - 467
  • [47] CLINICAL-EVALUATION OF A CRYPTOCOCCAL ANTIGEN LATEX AGGLUTINATION-TEST FOR DIAGNOSIS OF CRYPTOCOCCOSIS IN CATS
    MEDLEAU, L
    MARKS, MA
    BROWN, J
    BORGES, WL
    JOURNAL OF THE AMERICAN VETERINARY MEDICAL ASSOCIATION, 1990, 196 (09) : 1470 - 1473
  • [48] Multisite Validation of Cryptococcal Antigen Lateral Flow Assay and Quantification by Laser Thermal Contrast
    Boulware, David R.
    Rolfes, Melissa A.
    Rajasingham, Radha
    von Hohenberg, Maximilian
    Qin, Zhenpeng
    Taseera, Kabanda
    Schutz, Charlotte
    Kwizera, Richard
    Butler, Elissa K.
    Meintjes, Graeme
    Muzoora, Conrad
    Bischof, John C.
    Meya, David B.
    EMERGING INFECTIOUS DISEASES, 2014, 20 (01) : 45 - 53
  • [49] Cost-effectiveness analysis and budgetary impact of the Cryptococcal Antigen Lateral Flow Assay (CRAG-LFA) implementation for the screening and diagnosis of cryptococcosis in asymptomatic people living with HIV in Brazil
    de Mello Vianna, Cid Manso
    Gonzalez Mosegui, Gabriela Bittencourt
    REVISTA DO INSTITUTO DE MEDICINA TROPICAL DE SAO PAULO, 2021, 63
  • [50] The cryptococcal antigen lateral flow assay: A point-of-care diagnostic at an opportune time
    Tang, Michele W.
    Clemons, Karl V.
    Katzenstein, David A.
    Stevens, David A.
    CRITICAL REVIEWS IN MICROBIOLOGY, 2016, 42 (04) : 634 - 642
12345