Studies towards the total synthesis of ouabagenin

被引:17
|
作者
Chen, L [1 ]
Deslongchamps, P [1 ]
机构
[1] Univ Sherbrooke, Inst Pharmacol Sherbrooke, Dept Chim, Organ Synth Lab, Sherbrooke, PQ J1H 5N4, Canada
关键词
organic chemistry; synthesis; cycloaddition; polycyclization; Michael reaction; Diels-Alder reaction; steroids; oubain; ouabagenin; natural products;
D O I
10.1139/V05-042
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
An anionic cyclization strategy developed in our laboratory was used to produce a versatile and convergent synthesis of an advanced tetracyclic intermediate for the construction of ouabagenin and closely related analogs.
引用
收藏
页码:728 / 740
页数:13
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