Quinolone analogues 8.: Synthesis of 3-aminopyridazino[3,4-b]quinoxalin-4(1H)-one

被引：7
|
作者：
Kurasawa, Y [1 ]
Kawase, A
Takizawa, J
Maesaki, Y
Kaji, E
Okamoto, Y
Kim, HS
机构：
[1] Kitasato Univ, Sch Pharmaceut Sci, Minato Ku, Tokyo 1088641, Japan
[2] Kitasato Univ, Ctr Nat Sci, Sagamihara, Kanagawa 2288555, Japan
[3] Catholic Univ Taegu, Dept Chem, Gyongsan 712702, South Korea
来源：
JOURNAL OF HETEROCYCLIC CHEMISTRY | 2005年 / 42卷 / 04期
关键词：
D O I：
10.1002/jhet.5570420412
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
The 3-amino-1-methylpyridazino[3,4-b]quinoxalin-4(1H)-one 6 and N-(1,4-dihydro-1-methyl-4-oxopyridazino[3,4-b]quinoxalin-3-yl)carbamates 17a,b were synthesized from the 1,4-dihydro-1-methyl-4-oxopyridazino[3,4-b]quinoxaline-3-carboxylate 1b via the 1,5-dihydro-4-hydroxy-1-methylpyridazino[3,4-b]quinoxaline-3-carbohydrazide 13b and then 1,4-dihydro-1-methyl-4-oxopyridazino[3,4-b]quinoxaline-3-carboxazide 8. Heating of compound 13b and arylaldehydes afforded the 1,4-dihydro-1-methyl-4-oxopyridazino[3,4-b]quinoxaline-3-carbo(2-arylmethylene)hydrazides 14a-d.
引用
收藏
页码：551 / 556
页数：6
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