A mild and efficient one-pot synthesis of 2-dihydroimidazoles from aldehydes

被引：122
|
作者：
Fujioka, H [1 ]
Murai, K [1 ]
Ohba, Y [1 ]
Hiramatsu, A [1 ]
Kita, Y [1 ]
机构：
[1] Osaka Univ, Grad Sch Pharmaceut Sci, Suita, Osaka 5650871, Japan
来源：
TETRAHEDRON LETTERS | 2005年 / 46卷 / 13期
关键词：
dihydroimidazole; aldehyde; 1,2-diamine; N; N-Acetal; N-halosuccinimide; mild reaction;
D O I：
10.1016/j.tetlet.2005.02.025
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
The reactions of various aldehydes and 1,2-diamines followed by NXS treatment proceed at 0 degrees C to give the corresponding dihydroimidazoles in high yields. The reaction is mild, and many functional groups such as halogens, nitrites, and esters can exist. (c) 2005 Elsevier Ltd. All rights reserved.
引用
收藏
页码：2197 / 2199
页数：3
相关论文
共 50 条
  • [31] Mild and efficient one-pot synthesis of 2-imidazolines from nitriles using sodium hydrosulfide as catalyst
    Sun, Min
    Wei, Hong-Tao
    Li, Dong
    Zheng, You-Guang
    Cai, Jin
    Ji, Min
    SYNTHETIC COMMUNICATIONS, 2008, 38 (18) : 3151 - 3158
  • [32] Efficient one-pot synthesis of 2-aryldihydrobenzofuran
    Pan, CF
    Ma, ZX
    Yu, J
    Zhang, ZH
    Hui, AL
    Wang, ZY
    SYNLETT, 2005, (12) : 1922 - 1926
  • [33] A one-pot synthesis of tetrahydroisoquinolonic acids from aldehydes and amines in trimethylorthoformate
    Yu, NF
    Poulain, R
    Gesquiere, JC
    SYNLETT, 2000, (03) : 355 - 356
  • [34] Diacetoxyiodobenzene Mediated One-Pot Synthesis of Diverse Carboxamides from Aldehydes
    Prasad, Virendra
    Kale, Raju R.
    Mishra, Bhuwan B.
    Kumar, Dhananjay
    Tiwari, Vinod K.
    ORGANIC LETTERS, 2012, 14 (12) : 2936 - 2939
  • [35] A ONE-POT STEREOSELECTIVE SYNTHESIS OF HYDROXY-KETENEDITHIOACETALS FROM ALDEHYDES
    TCHERTCHIAN, S
    VALLEE, Y
    TETRAHEDRON LETTERS, 1995, 36 (35) : 6225 - 6226
  • [36] A green, mild and efficient one-pot method for the synthesis of sulfonamides from thiols and disulfides in water
    Massah, Ahmad Reza
    Sayadi, Safura
    Ebrahimi, Sara
    RSC ADVANCES, 2012, 2 (16): : 6606 - 6616
  • [37] Highly Efficient Microwave-assisted One-Pot Synthesis of Aromatic Nitriles from Aromatic Aldehydes
    P. L. Pujari
    P. V. Thorat
    A. B. Mahipal
    R. S. Bhondwe
    Russian Journal of Organic Chemistry, 2019, 55 : 702 - 706
  • [38] An efficient one-pot synthesis of (+)-deoxypyridinoline
    Adamczyk, M
    Johnson, DD
    Reddy, RE
    TETRAHEDRON LETTERS, 1999, 40 (51) : 8993 - 8994
  • [39] An efficient one-pot synthesis of flavones
    Chee, Chin Fei
    Buckle, Michael J. C.
    Abd Rahman, Noorsaadah
    TETRAHEDRON LETTERS, 2011, 52 (24) : 3120 - 3123
  • [40] An efficient one-pot synthesis of bisalkylthioarenes
    Charoonniyomporn, P
    Thongpanchang, T
    Witayakran, S
    Thebtaranonth, Y
    Phillips, KES
    Katz, TJ
    TETRAHEDRON LETTERS, 2004, 45 (03) : 457 - 459
12345