Red-emitting fluorogenic BODIPY-tetrazine probes for biological imaging

被引：14

作者：

Chen, Lei ^{[1
]}

Li, Fei ^{[2
]}

Li, Yan ^{[1
]}

Yang, Jun ^{[2
]}

Li, Yongjun ^{[1
]}

He, Bin ^{[1
]}

机构：

[1] Guizhou Med Univ, Engn Res Ctr Dev & Applicat Ethn Med & TCM, State Key Lab Funct & Applicat Med Plants, Sch Pharm,Minist Educ,Guizhou Prov Key Lab Pharma, Guiyang 550004, Peoples R China

[2] Shaanxi Normal Univ, Sch Chem & Chem Engn, Key Lab Macromol Sci Shaanxi Prov, Minist Educ,Key Lab Appl Surface & Colloid Chem, Changan Campus 620,West Changan Ave, Xian 710119, Peoples R China

来源：

CHEMICAL COMMUNICATIONS | 2021年 / 58卷 / 02期

基金：

中国国家自然科学基金;

关键词：

FLUORESCENCE; DERIVATIVES; LIGATION;

D O I：

10.1039/d1cc05863k

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A series of new BODIPY-tetrazine derivatives have been developed with a twist intramolecular charge transfer (TICT) state in polar solvents, which is an electron transfer process that occurs upon photoexcitation in a molecule that usually consists of an electron donor and acceptor linked by a single bond. Among them, the BODIPY-tetrazine derivative 6i was stable towards long-term storage and red-emitting with excellent performance, and was further used to image trans-cyclooctene-labeled lipids in mammalian cells and cyclopropene-labeled sugars in cancer cells under no-wash conditions.

引用

页码：298 / 301

页数：4

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