Red-emitting fluorogenic BODIPY-tetrazine probes for biological imaging

被引:14
|
作者
Chen, Lei [1 ]
Li, Fei [2 ]
Li, Yan [1 ]
Yang, Jun [2 ]
Li, Yongjun [1 ]
He, Bin [1 ]
机构
[1] Guizhou Med Univ, Engn Res Ctr Dev & Applicat Ethn Med & TCM, State Key Lab Funct & Applicat Med Plants, Sch Pharm,Minist Educ,Guizhou Prov Key Lab Pharma, Guiyang 550004, Peoples R China
[2] Shaanxi Normal Univ, Sch Chem & Chem Engn, Key Lab Macromol Sci Shaanxi Prov, Minist Educ,Key Lab Appl Surface & Colloid Chem, Changan Campus 620,West Changan Ave, Xian 710119, Peoples R China
基金
中国国家自然科学基金;
关键词
FLUORESCENCE; DERIVATIVES; LIGATION;
D O I
10.1039/d1cc05863k
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
A series of new BODIPY-tetrazine derivatives have been developed with a twist intramolecular charge transfer (TICT) state in polar solvents, which is an electron transfer process that occurs upon photoexcitation in a molecule that usually consists of an electron donor and acceptor linked by a single bond. Among them, the BODIPY-tetrazine derivative 6i was stable towards long-term storage and red-emitting with excellent performance, and was further used to image trans-cyclooctene-labeled lipids in mammalian cells and cyclopropene-labeled sugars in cancer cells under no-wash conditions.
引用
收藏
页码:298 / 301
页数:4
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