Acute generalized exanthematous pustulosis induced by phenobarbital

被引：1
|
作者：
Hedhli, A. [1 ]
Mjid, M. [1 ]
Cheikhrouhou, S. [1 ]
Slim, A. [1 ]
Ben Khaled, S. [1 ]
Ouahchi, Y. [1 ]
Beji, M. [1 ]
Toujani, S. [1 ]
Merai, S. [1 ]
机构：
[1] CHU Rabta, Serv Pneumol, UR 12SP06, Tunis, Tunisia
来源：
REVUE FRANCAISE D ALLERGOLOGIE | 2018年 / 58卷 / 06期
关键词：
Acute generalized exanthematous pustulosis; Phenobarbital; Drug eruption; Antiepileptics; Delayed hypersensitivity reaction;
D O I：
10.1016/j.reval.2018.06.001
中图分类号：
R392 [医学免疫学];
学科分类号：
100102 ;
摘要：
Acute generalized exanthematous pustulosis (AGEP) is a severe eruption chiefly induced by drugs. We report a rare case of AGEP occurring after treatment with phenobarbital. A 22-year-old woman developed febrile exanthematous pustulosis eruption after treatment with phenobarbital for cerebral tuberculoma. A diagnosis of phenobarbital-induced AGEP was made on the basis of a skin biopsy and of likely intrinsic imputability of I3 (C3 S3). Complete regression of lesions was obtained after withdrawal of the phenobarbital. (C) 2018 Elsevier Masson SAS. All rights reserved.
引用
收藏
页码：475 / 477
页数：3
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