Trans-synaptic plasticity: Presynaptic initiation, postsynaptic memory

被引：2
|
作者：
Wan, Qin [1 ]
Abrams, Thomas W. [1 ,2 ,3 ]
机构：
[1] Univ Maryland, Sch Med, Dept Pharmacol, Baltimore, MD 21201 USA
[2] Univ Maryland, Sch Med, Dept Anesthesiol, Baltimore, MD 21201 USA
[3] Univ Maryland, Sch Med, Program Neurosci, Baltimore, MD 21201 USA
来源：
CURRENT BIOLOGY | 2008年 / 18卷 / 05期
关键词：
D O I：
10.1016/j.cub.2007.12.046
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
A novel mechanism of persistent facilitation induced by serotonin at Aplysia synapses depends upon rapid postsynaptic protein synthesis and increased responsiveness to glutamate; whereas the memory for this synaptic change is postsynaptic, the initiating signal may be an increase in spontaneous release of glutamate from the presynaptic terminals.
引用
收藏
页码：R220 / R223
页数：4
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