Increasing Endothelial Insulin Sensitivity Rescues Vascular Function and Repair in Systemic Insulin Resistance by Restoring Nitric Oxide Bioavailability and Improving Endothelial Cell Migration

被引:0
|
作者
Sengupta, Anshuman
Yuldasheva, Nadira
Viswambharan, Hema
Galloway, Stacey
Mughal, Romana
Mercer, Ben
Ali, Noman
Walker, Andrew
Aziz, Amir
Smith, Jessica
Skromna, Anna
Makava, Natallia
Kearney, Mark
Cubbon, Richard
机构
关键词
Insulin Sensitivity; Vascular Repair; Endothelial Function;
D O I
暂无
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
13492
引用
收藏
页数:4
相关论文
共 50 条
  • [31] ENHANCING ENDOTHELIAL INSULIN SENSITIVITY REDUCES NITRIC OXIDE BIOAVAILABILITY: A ROLE FOR NADPH OXIDASE-DERIVED REACTIVE OXYGEN SPECIES
    Viswambharan, H.
    Sukumar, P.
    Gage, M. C.
    Yuldasheva, N.
    Skromna, A.
    Imrie, H.
    Galloway, S.
    Smith, J.
    Cubbon, R.
    Wheatcroft, S. B.
    Kearney, M. T.
    HEART, 2012, 98 : A59 - A60
  • [32] The association of clinical characteristics with insulin induced endothelial cell nitric oxide phosphorylation
    Behrooz, Leili
    Hamburg, Naomi
    VASCULAR MEDICINE, 2022, 27 (06) : 643 - 643
  • [33] PLASMA FROM PREPUBERTAL OBESE CHILDREN IMPAIRS ENDOTHELIAL NITRIC OXIDE BIOAVAILABILITY: LINKING INSULIN RESISTANCE, INFLAMMATION AND ER STRESS
    Chiarelli, Francesco
    Di Pietro, Natalia
    Pandolfi, Assunta
    Mohn, Angelika
    HORMONE RESEARCH IN PAEDIATRICS, 2017, 88 : 322 - 322
  • [34] Adaptation of -Cell and Endothelial Function to Carbohydrate Loading: Influence of Insulin Resistance
    Hurwitz, Barry E.
    Schneiderman, Neil
    Marks, Jennifer B.
    Mendez, Armando J.
    Gonzalez, Alex
    Llabre, Maria M.
    Smith, Steven R.
    Bizzotto, Roberto
    Santini, Eleonora
    Manca, Maria Laura
    Skyler, Jay S.
    Mari, Andrea
    Ferrannini, Ele
    DIABETES, 2015, 64 (07) : 2550 - 2559
  • [35] Regulation of endothelial constitutive nitric oxide synthase gene expression in endothelial cells and in vivo A specific vascular action of insulin
    Kuboki, K
    Jiang, ZY
    Takahara, N
    Ha, SW
    Igarashi, M
    Yamauchi, T
    Feener, EP
    Herbert, TP
    Rhodes, CJ
    King, GL
    CIRCULATION, 2000, 101 (06) : 676 - 681
  • [36] Acute nitric oxide synthase inhibition enhances trans-endothelial insulin efflux and muscle insulin sensitivity in vivo
    Williams, Ian M.
    McClatchey, Penn Mason
    Mignemi, Nicholas A.
    McGuinness, Owen P.
    Wasserman, David H.
    FASEB JOURNAL, 2018, 32 (01):
  • [37] Exercise training, vascular endothelial function and insulin sensitivity in patients with type 2 diabetes
    De Filippis, E
    Miyazaki, Y
    Cersosimo, E
    Cusi, K
    Consoli, A
    Pandolfi, A
    Capani, F
    Defronzo, R
    Mandarino, L
    DIABETES, 2003, 52 : A238 - A238
  • [38] The effect of nitric oxide on insulin binding, internalization and insulin receptor recycling in bovine aortic endothelial cell (BAEC)
    Cha, BY
    Kwon, HS
    Hong, OK
    Lee, JM
    Son, HS
    Yoon, KH
    Kang, MI
    Lee, KW
    Son, HY
    Kang, SK
    DIABETES, 2002, 51 : A571 - A572
  • [39] Endothelial nitric oxide production and insulin sensitivity - A physiological link with implications for pathogenesis of cardiovascular disease
    Petrie, JR
    Ueda, S
    Webb, DJ
    Elliott, HL
    Connell, JMC
    CIRCULATION, 1996, 93 (07) : 1331 - 1333
  • [40] Nitric oxide induces vascular endothelial cell migration by modulating matrix metalloproteinase activities
    Lopez-Rivera, E
    Lizarbe, TR
    Lamas, S
    Zaragoza, C
    CIRCULATION, 2004, 110 (17) : 121 - 121