Increasing Endothelial Insulin Sensitivity Rescues Vascular Function and Repair in Systemic Insulin Resistance by Restoring Nitric Oxide Bioavailability and Improving Endothelial Cell Migration

被引:0
|
作者
Sengupta, Anshuman
Yuldasheva, Nadira
Viswambharan, Hema
Galloway, Stacey
Mughal, Romana
Mercer, Ben
Ali, Noman
Walker, Andrew
Aziz, Amir
Smith, Jessica
Skromna, Anna
Makava, Natallia
Kearney, Mark
Cubbon, Richard
机构
关键词
Insulin Sensitivity; Vascular Repair; Endothelial Function;
D O I
暂无
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
13492
引用
收藏
页数:4
相关论文
共 50 条
  • [21] Hyperuricemia-induced endothelial insulin resistance: the nitric oxide connection
    Bahadoran, Zahra
    Mirmiran, Parvin
    Kashfi, Khosrow
    Ghasemi, Asghar
    PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY, 2022, 474 (01): : 83 - 98
  • [22] Impaired endothelial relaxation associated with insulin resistance is not due to nitric oxide
    Winecoff, AP
    Li, S
    Ujhelyi, MR
    JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 1997, 29 (02) : 7174 - 7174
  • [23] Hyperuricemia-induced endothelial insulin resistance: the nitric oxide connection
    Zahra Bahadoran
    Parvin Mirmiran
    Khosrow Kashfi
    Asghar Ghasemi
    Pflügers Archiv - European Journal of Physiology, 2022, 474 : 83 - 98
  • [24] Uric acid induces endothelial dysfunction by vascular insulin resistance associated with the impairment of nitric oxide synthesis
    Choi, You-Jin
    Yoon, Yujin
    Lee, Kang-Yo
    Hien, Tran Thi
    Kang, Keon Wook
    Kim, Kyong-Cheol
    Lee, Jeewoo
    Lee, Moo-Yeol
    Lee, Seung Mi
    Kang, Duk-Hee
    Lee, Byung-Hoon
    FASEB JOURNAL, 2014, 28 (07): : 3197 - 3204
  • [25] URIC ACID INDUCES ENDOTHELIAL DYSFUNCTION BY VASCULAR INSULIN RESISTANCE ASSOCIATED WITH THE IMPAIRMENT OF NITRIC OXIDE SYNTHESIS
    Choi, Y.
    Yoon, Y.
    Lee, K.
    Kang, K.
    Lee, B.
    BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY, 2014, 115 : 52 - 52
  • [26] Nitric oxide mediates the mitogenic effects of insulin and vascular endothelial growth factor but not of leptin in endothelial cells
    Józkowicz, A
    Pankiewicz, J
    Dulak, J
    Partyka, L
    Wybranska, I
    Huk, I
    Dembinska-Kiec, A
    ACTA BIOCHIMICA POLONICA, 1999, 46 (03) : 703 - 715
  • [27] Hematopoietic Cell-Expressed Endothelial Nitric Oxide Protects the Liver From Insulin Resistance
    Dick, Brian P.
    McMahan, Ryan
    Knowles, Taft
    Becker, Lev
    Gharib, Sina A.
    Vaisar, Tomas
    Wietecha, Tomasz
    O'Brien, Kevin D.
    Bornfeldt, Karin E.
    Chait, Alan
    Kim, Francis
    ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, 2020, 40 (03) : 670 - 681
  • [28] INSULIN RESISTANCE REDUCES CIRCULATING ENDOTHELIAL PROGENITOR CELLS AND IMPAIRS ENDOTHELIAL REPAIR FOLLOWING VASCULAR INJURY
    Kahn, M.
    Cubbon, R.
    Abbas, A.
    Visvambharan, H.
    Yuldasheva, N.
    Rajwani, A.
    Gage, M.
    Imrie, H.
    Kearney, M.
    Wheatcroft, S.
    HEART, 2009, 95 (22)
  • [29] Insulin resistance, hyperlipidemia, and hypertension in mice lacking endothelial nitric oxide synthase
    Duplain, H
    Burcelin, R
    Sartori, C
    Cook, S
    Egli, M
    Lepori, M
    Vollenweider, P
    Pedrazzini, T
    Nicod, P
    Thorens, B
    Scherrer, U
    CIRCULATION, 2001, 104 (03) : 342 - 345
  • [30] Endothelial Cell Activation, Impaired Nitric Oxide Bioavailability and Reduced Endothelial Repair Capacity After Anger Provocation
    Rosenberg, Leah B.
    Zhao, Shuqing
    Cholankeril, Matthew
    Iyer, Padmini
    Hong, Sangbeen
    Burg, Matthew M.
    Shimbo, Daichi
    CIRCULATION, 2009, 120 (18) : S461 - S461