Increased numbers of interleukin-12-producing cells in human tuberculosis

被引：22

作者：

Munk, ME ^{[1
]}

Mayer, P ^{[1
]}

Anding, P ^{[1
]}

Feldmann, K ^{[1
]}

Kaufmann, SHE ^{[1
]}

机构：

[1] LANDESVERSICHERUNGSANSTALT,ZENT KRANKHENHAUS,GAUTING,GERMANY

来源：

INFECTION AND IMMUNITY | 1996年 / 64卷 / 03期

关键词：

D O I：

10.1128/IAI.64.3.1078-1080.1996

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Numbers of interleukin-12 (IL-12)-producing cells were quantitated in the peripheral blood of healthy donors and tuberculosis patients by the ELISPOT assay. We observed that (i) stimulation with mycobacteria increases numbers of IL-12 producers from healthy donors and (ii) tuberculosis patients have larger numbers of IL-12 producers than healthy donors. Our data emphasize the importance of IL-12 in immunity to tuberculosis.

引用

页码：1078 / 1080

页数：3

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