Increased numbers of interleukin-12-producing cells in human tuberculosis

被引：22
|
作者：
Munk, ME [1 ]
Mayer, P [1 ]
Anding, P [1 ]
Feldmann, K [1 ]
Kaufmann, SHE [1 ]
机构：
[1] LANDESVERSICHERUNGSANSTALT,ZENT KRANKHENHAUS,GAUTING,GERMANY
来源：
INFECTION AND IMMUNITY | 1996年 / 64卷 / 03期
关键词：
D O I：
10.1128/IAI.64.3.1078-1080.1996
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
Numbers of interleukin-12 (IL-12)-producing cells were quantitated in the peripheral blood of healthy donors and tuberculosis patients by the ELISPOT assay. We observed that (i) stimulation with mycobacteria increases numbers of IL-12 producers from healthy donors and (ii) tuberculosis patients have larger numbers of IL-12 producers than healthy donors. Our data emphasize the importance of IL-12 in immunity to tuberculosis.
引用
收藏
页码：1078 / 1080
页数：3
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