Seven-membered ring formation through Grewe-cyclization

被引:9
|
作者
Lukács, A
Szabó, L
Hazai, L
Szantay, C
Mák, M
Gorka, A
Szántay, C
机构
[1] Budapest Univ Technol & Econ, Inst Organ Chem, H-1111 Budapest, Hungary
[2] Hungarian Acad Sci, Res Grp Alkaloid Chem, H-1111 Budapest, Hungary
[3] Gedeon Richter Chem Works Ltd, Spectroscop Res Div, H-1475 Budapest, Hungary
关键词
reduction; rearrangement; cyclization; benzazepines;
D O I
10.1016/S0040-4020(01)00497-5
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
The first example of seven-membered ring formation using Grewe-cyclization of cyclohexene derivatives (3b and c) yielding spiro-substituted benzo[c]azepines (9b and c) is presented. (C) 2001 Elsevier Science Ltd. All rights reserved.
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页码:5843 / 5850
页数:8
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