Antimicrobial activity of new coumarin derivatives

被引：1
|
作者：
Kawase, M [1 ]
Varu, B
Shah, A
Motohashi, N
Tani, S
Saito, S
Debnath, S
Mahapatra, S
Dastidar, SG
Chakrabarty, AN
机构：
[1] Josai Univ, Fac Pharmaceut Sci, Sakado, Saitama 3500295, Japan
[2] Saurashtra Univ, Dept Chem, Rajkot 360005, Gujarat, India
[3] Meiji Pharmaceut Univ, Tokyo, Japan
[4] Jadavpur Univ, Dept Pharmaceut Technol, Div Microbiol, Kolkata 700032, W Bengal, India
[5] Univ Calcutta, Coll Med, Dept Med Microbiol & Parasitol, Kolkata, W Bengal, India
来源：
ARZNEIMITTELFORSCHUNG-DRUG RESEARCH | 2001年 / 51卷 / 01期
关键词：
coumarin derivatives; anti-Helicobacter pylori activity; antimicrobial activity; in vitro studies; synthesis;
D O I：
暂无
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
A preliminary exploration of coumarin analogs as novel antimicrobial agents was carried out to determine the basic features of the structure responsible for the observed biological activity. The substituents ester or carboxylic acid on the coumarin ring were needed to have potent inhibitory activity against both Gram-positive and Gram-negative bacteria. The presence of phenolic hydroxyl group and/or carboxylic acid was necessary to possess higher activity against Helicobacter pylori.
引用
收藏
页码：67 / 71
页数：5
相关论文
共 50 条
  • [41] Synthesis of Coumarin-Triazene-Alkoxyphenyl Derivatives and In Silico Simulation for Potential Antimicrobial Activity
    Mortadza, N. A.
    Madiahlagan, E.
    Ngaini, Z.
    RUSSIAN JOURNAL OF ORGANIC CHEMISTRY, 2025, 61 (01) : 124 - 132
  • [42] Ecofriendly microwave enhanced synthesis of imidazole derivatives containing coumarin moiety & their antimicrobial activity
    Maroliwala, Jigisha A.
    Naik, Bhanvesh
    Desai, K. R.
    INDIAN JOURNAL OF HETEROCYCLIC CHEMISTRY, 2008, 17 (04) : 363 - 364
  • [43] Antimicrobial Activity of a New Series of Benzimidazole Derivatives
    Ozkay, Yusuf
    Tunali, Yagmur
    Karaca, Hulya
    Isikdag, Ilhan
    ARCHIVES OF PHARMACAL RESEARCH, 2011, 34 (09) : 1427 - 1435
  • [44] SYNTHESIS AND ANTIMICROBIAL ACTIVITY OF NEW PYRAZOLINE DERIVATIVES
    Ozdemir, A.
    Turan-Zitouni, G.
    Kaplancikli, Z. A.
    Altintop, M. D.
    Demirci, F.
    EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES, 2011, 44 : 165 - 166
  • [45] Antimicrobial Activity of Some New Oxadiazole Derivatives
    Muhi-eldeen, Zuhair
    Juma'a, Ghada
    Al-kaissi, Elham
    Nouri, Lina
    JORDAN JOURNAL OF CHEMISTRY, 2008, 3 (03) : 233 - 243
  • [46] Synthesis and the antimicrobial activity of new isothiazolone derivatives
    Zhang, PY
    Yu, X
    Chen, ZY
    Wang, YL
    Chen, SH
    Yang, ZR
    Hou, RT
    CHINESE JOURNAL OF ORGANIC CHEMISTRY, 2005, 25 (09) : 1142 - 1146
  • [47] SYNTHESIS AND ANTIMICROBIAL ACTIVITY OF NEW BENZOFURANYLPYRIDINE DERIVATIVES
    HISHMAT, OH
    ABDELGALIL, FM
    FARRAG, DS
    PHARMAZIE, 1990, 45 (10): : 793 - 795
  • [48] Synthesis and antimicrobial activity of new triazolopyrimidinecarbonitrile derivatives
    Kadry, Azza M.
    Aal, Eatedal H. Abdel
    Abdel-Fattah, Hanan A.
    Al-Mahmoudy, Amany M.
    ARKIVOC, 2008, : 127 - 134
  • [49] Synthesis and antimicrobial activity of new glucosamine derivatives
    Anh, Le Duc
    Bao, Ninh Duc
    Duc, Le Viet
    Van Chinh, Luu
    Cuong, Nguyen Manh
    Thuy, Dinh Thi Thu
    Hung, Truong Ngoc
    VIETNAM JOURNAL OF CHEMISTRY, 2023, 61 (S2) : 124 - 130
  • [50] New Class of Triazole Derivatives and Their Antimicrobial Activity
    Maddila, Suresh
    Jonnalagadda, Sreekanth B.
    LETTERS IN DRUG DESIGN & DISCOVERY, 2012, 9 (07) : 687 - 693
12345