Micro Patterning Processes for Thin Film Nitinol Endografts and Evaluation of Endothelialization in Swine Model

被引：0
|
作者：
Chun, Youngjae [1 ]
Levi, Daniel S. [2 ]
Mohanchandra, K. P. [1 ]
Tulloch, Allan W. [3 ]
Rigberg, David A. [3 ]
Vinuela, Fernando [4 ]
Vinuela, Fernando, Jr. [5 ]
Carman, Gregory P. [1 ]
机构：
[1] Univ Calif Los Angeles, Dept Mech & Aerosp Engn, 32-135,Engn 4, Los Angeles, CA 90095 USA
[2] Univ Calif Los Angeles, Mattel Childrens Hosp, Pediat Cardiol, Los Angeles, CA 90095 USA
[3] Univ Calif Los Angeles, David Geffen Sch Med, Div Vasc Surg, Los Angeles, CA 90095 USA
[4] Univ Calif Los Angeles, David Geffen Sch Med, Radiol Sci, Los Angeles, CA 90095 USA
[5] Univ Calif Los Angeles, David Geffen Sch Med, Rigler Ctr, Radiolo Sci & Neurosurg, Los Angeles, CA 90095 USA
来源：
HEALTH MONITORING OF STRUCTURAL AND BIOLOGICAL SYSTEMS 2010, PTS 1 AND 2 | 2010年 / 7650卷
关键词：
thin film nitinol; endovascular device; wet etching; lift-off; endothelial tissue; thrombosis;
D O I：
10.1117/12.847588
中图分类号：
O43 [光学];
学科分类号：
070207 ; 0803 ;
摘要：
Micro features were created in thin film nitinol using a novel lift-off process to create an endovascular biomedical device. This manuscript describes fabrication problems with wet etching and introduces an effective way, named "Lift-off" process to solve undercut and non-uniform pattern issues. Two lift-off processes (i.e., lift-off I and II) are discussed. Lift-off I process has fracture issues and the film peels off the substrate due to high aspect ratio post structures. Lift-off II process use the film on the top of the Si substrate to fabricate various shape patterns (i.e., ellipse, diamond, circle, square, etc.) in the range of 5 similar to 60 mu m. The lift-off II process shows smooth and well aligned micro patterns in thin film nitinol. In-vivo tests in swine were performed to evaluate the endothelial tissue growth through fabricated micro patterns. Angiography and SEM images show patency of the artery and a uniform endothelial layer covering the device without thromobosis.
引用
收藏
页数：11
相关论文
共 50 条
  • [31] Characterization of Stress-Controlled a-IGZO Thin Films and their Applications to Thin-Film Transistor and Micro-Electromechanical System Processes
    Iwamatsu, Shinnosuke
    Takechi, Kazushige
    Abe, Yutaka
    Yahagi, Toru
    Tanabe, Hiroshi
    Kobayashi, Seiya
    PROCEEDINGS OF 2013 TWENTIETH INTERNATIONAL WORKSHOP ON ACTIVE-MATRIX FLATPANEL DISPLAYS AND DEVICES (AM-FPD 13): TFT TECHNOLOGIES AND FPD MATERIALS, 2013, : 133 - 136
  • [32] Evaluation of Gas Permeability for Micro-scale Thin Polymer Film with Encapsulated MEMS Damped Oscillator
    Gando, Ryunosuke
    Nakamura, Naofumi
    Hayashi, Yumi
    Ono, Daiki
    Masunishi, Kei
    Tomizawa, Yasushi
    Yamazaki, Hiroaki
    Ikehashi, Tamio
    Sugizaki, Yoshiaki
    Shibata, Hideki
    2014 IEEE SENSORS, 2014,
  • [33] Stress evaluation in thin films: Micro-focus synchrotron X-ray diffraction combined with focused ion beam patterning for do evaluation
    Baimpas, Nikolaos
    Le Bourhis, Eric
    Eve, Sophie
    Thiaudiere, Dominique
    Hardie, Christopher
    Korsunsky, Alexander M.
    THIN SOLID FILMS, 2013, 549 : 245 - 250
  • [34] Marangoni effect induced micro/nano-patterning on Sb2Te3 phase change thin film by laser pulse
    Dun, Aihuan
    Wei, Jingsong
    Gan, Fuxi
    APPLIED PHYSICS A-MATERIALS SCIENCE & PROCESSING, 2011, 103 (01): : 139 - 147
  • [35] Numerical Model of Thermal Processes in Domain of Thin Film Subjected to a Cyclic External Heat Flux
    Mochnacki, Bohdan
    Ciesielski, Mariusz
    THERMEC 2011, PTS 1-4, 2012, 706-709 : 1460 - +
  • [36] UV micro-imprint patterning for tunable light trapping in p-i-n thin-film silicon solar cells
    Wang, Yanfeng
    Zhang, Xiaodan
    Han, Bing
    Bai, Lisha
    Zhao, Huixu
    Yang, Fu
    Liang, Junhui
    Huang, Qian
    Chen, Xinliang
    Zhao, Ying
    APPLIED SURFACE SCIENCE, 2015, 355 : 14 - 18
  • [37] Direct patterning of tris-(8-hydroxyquinoline)-aluminum (III) thin film at submicron scale by modified micro-transfer molding
    Cavallini, M
    Murgia, M
    Biscarini, F
    MATERIALS SCIENCE & ENGINEERING C-BIOMIMETIC AND SUPRAMOLECULAR SYSTEMS, 2002, 19 (1-2): : 275 - 278
  • [38] Marangoni effect induced micro/nano-patterning on Sb2Te3 phase change thin film by laser pulse
    Aihuan Dun
    Jingsong Wei
    Fuxi Gan
    Applied Physics A, 2011, 103 : 139 - 147
  • [39] Nano/micro-patterning of anatase TiO2 thin film from an aqueous solution by site-selective elimination method
    Masuda, Yoshitake
    Saito, Noriko
    Hoffmann, Rudolf
    De Guire, Mark R.
    Koumoto, Kunihito
    SCIENCE AND TECHNOLOGY OF ADVANCED MATERIALS, 2003, 4 (05) : 461 - 467
  • [40] Micro-/poly-crystalline silicon materials for thin film photovoltaic devices: Deposition processes and growth mechanisms
    Rath, JK
    PHOTOVOLTAIC AND PHOTOACTIVE MATERIALS - PROPERTIES, TECHNOLOGY AND APPLICATIONS, 2002, 80 : 157 - 170
12345