Chimeric peptide beacons: a direct polypeptide analog of DNA molecular beacons

被引：31
|
作者：
Oh, Kenneth J. [1 ]
Cash, Kevin J. [2 ]
Lubin, Arica A. [1 ]
Plaxco, Kevin W. [1 ,3 ]
机构：
[1] Univ Calif Santa Barbara, Dept Chem & Biochem, Santa Barbara, CA 93106 USA
[2] Univ Calif Santa Barbara, Dept Chem Engn, Santa Barbara, CA 93106 USA
[3] Univ Calif Santa Barbara, Interdept Program Biomol Sci & Engn, Santa Barbara, CA 93106 USA
来源：
CHEMICAL COMMUNICATIONS | 2007年 / 46期
关键词：
D O I：
10.1039/b709776j
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
We have developed a new biosensor architecture, which is comprised of a polypeptide-peptide nucleic acid tri-block copolymer and which we have termed chimeric peptide beacons (CPB), that generates an optical output via a mechanism analogous to that employed in DNA-based molecular beacons.
引用
收藏
页码：4869 / 4871
页数：3
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