Chimeric peptide beacons: a direct polypeptide analog of DNA molecular beacons

被引：31

作者：

Oh, Kenneth J. ^{[1
]}

Cash, Kevin J. ^{[2
]}

Lubin, Arica A. ^{[1
]}

Plaxco, Kevin W. ^{[1
,3
]}

机构：

[1] Univ Calif Santa Barbara, Dept Chem & Biochem, Santa Barbara, CA 93106 USA

[2] Univ Calif Santa Barbara, Dept Chem Engn, Santa Barbara, CA 93106 USA

[3] Univ Calif Santa Barbara, Interdept Program Biomol Sci & Engn, Santa Barbara, CA 93106 USA

来源：

CHEMICAL COMMUNICATIONS | 2007年 / 46期

关键词：

D O I：

10.1039/b709776j

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

We have developed a new biosensor architecture, which is comprised of a polypeptide-peptide nucleic acid tri-block copolymer and which we have termed chimeric peptide beacons (CPB), that generates an optical output via a mechanism analogous to that employed in DNA-based molecular beacons.

引用

页码：4869 / 4871

页数：3

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