Synthesis and antimicrobial activity of 2-Alkyl/aryl-5-(pyrid-4-yl)-1,3,4-oxadiazole

被引：0
|
作者：
Ingole, Priyadarshani S. [1 ]
Mohane, S. R. [1 ]
Berad, B. N. [1 ]
机构：
[1] Shri Shivaji Sci Coll, Dept Chem, Amravati 444603, India
来源：
ASIAN JOURNAL OF CHEMISTRY | 2007年 / 19卷 / 04期
关键词：
2-alkyl/aryl-5-(pyrid4-yl)1,3,4-oxadiazole; synthesis; antimicrobial activity;
D O I：
暂无
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Some new 2-substituted-5-(pyrid-4-yl)-1,3,4-oxadiazoles (IIIa-f) have been synthesized by oxidative cyclization of N-substituted isoniazids (IIa-f) with molecular iodine in presence of alkali in ethanolic medium. The latter have been synthesized by condensing isoniazid with different acid chlorides (Ia-f). All these compounds were screened for their antimicrobial activity against gram positive and gram negative microorganisms.
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页码：2683 / 2686
页数：4
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