Backbone and side-chain chemical shift assignments of MarH, a critical intermediary epimerase for biosynthesis of Maremycins in Streptomyces

被引：1

作者：

Liu, Bin ^{[1
,2
]}

Fang, Shiqi ^{[1
,2
]}

Ma, Xiaofang ^{[1
,2
]}

Bai, Zhiqiang ^{[1
,2
]}

Hu, Kaifeng ^{[1
]}

机构：

[1] Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, 132 Lanhei Rd, Kunming 650201, Yunnan, Peoples R China

[2] Univ Chinese Acad Sci, Beijing 100049, Peoples R China

来源：

BIOMOLECULAR NMR ASSIGNMENTS | 2018年 / 12卷 / 02期

基金：

中国国家自然科学基金;

关键词：

MarH; Epimerase; NMR; Chemical shift assignments; BIOMOLECULAR NMR; SUPERFAMILY;

D O I：

10.1007/s12104-018-9835-2

中图分类号：

Q6 [生物物理学];

学科分类号：

071011 ;

摘要：

MarH is an essential epimerase that catalyzes the isomerization of 3R--methyl-indolepyruvate (-MeInPy) to 3S--MeInPy, which is the important precursor for biosynthesis of Maremycins. Biophysical study of the structure of MarH would be informative for better understanding of its catalytic mechanism and feasible application of the enzyme in isomerization reaction. Here, we report the backbone and side-chain NMR chemical shift assignments of MarH, which lays a foundation for further structural and mechanical study of the enzyme.

引用

页码：335 / 338

页数：4

共 50 条

[21] Backbone and nearly complete side-chain chemical shift assignments reveal the human uncharacterized protein CXorf51A as intrinsically disordered
Christoph Wiedemann
Kingsley Benjamin Obika
Sandra Liebscher
Jan Jirschitzka
Oliver Ohlenschlãger
Frank Bordusa
Biomolecular NMR Assignments, 2021, 15 : 441 - 448
[22] Backbone and methyl side-chain resonance assignments of the single chain Fab fragment of trastuzumab
Gagne, Donald
Aramini, James M.
Aubin, Yves
BIOMOLECULAR NMR ASSIGNMENTS, 2024, 18 (02) : 119 - 128
[23] 1H, 13C and 15N backbone and side-chain chemical shift assignments for oxidized and reduced desulfothioredoxin
Edwige B. Garcin
Olivier Bornet
Laetitia Pieulle
Françoise Guerlesquin
Corinne Sebban-Kreuzer
Biomolecular NMR Assignments, 2010, 4 : 135 - 137
[24] Backbone and side-chain chemical shift assignments of full-length, apo, human Pin1, a phosphoprotein regulator with interdomain allostery
Alexandra Born
Parker J. Nichols
Morkos A. Henen
Celestine N. Chi
Dean Strotz
Peter Bayer
Shin-Ichi Tate
Jeffrey W. Peng
Beat Vögeli
Biomolecular NMR Assignments, 2019, 13 : 85 - 89
[25] 1H, 13C and 15N backbone and side-chain chemical shift assignments for oxidized and reduced desulfothioredoxin
Garcin, Edwige B.
Bornet, Olivier
Pieulle, Laetitia
Guerlesquin, Francoise
Sebban-Kreuzer, Corinne
BIOMOLECULAR NMR ASSIGNMENTS, 2010, 4 (02) : 135 - 137
[26] Backbone and side-chain chemical shift assignments of full-length, apo, human Pin1, a phosphoprotein regulator with interdomain allostery
Born, Alexandra
Nichols, Parker J.
Henen, Morkos A.
Chi, Celestine N.
Strotz, Dean
Bayer, Peter
Tate, Shin-Ichi
Peng, Jeffrey W.
Vogeli, Beat
BIOMOLECULAR NMR ASSIGNMENTS, 2019, 13 (01) : 85 - 89
[27] Protein-ligand structure guided by backbone and side-chain proton chemical shift perturbations
Aguirre, Clementine
ten Brink, Tim
Cala, Olivier
Guichou, Jean-Francois
Krimm, Isabelle
JOURNAL OF BIOMOLECULAR NMR, 2014, 60 (2-3) : 147 - 156
[28] Backbone and side-chain resonance assignments of the membrane localization domain from Pasteurellamultocida toxin
Michael C. Brothers
Brett Geissler
Grant S. Hisao
Karla J. F. Satchell
Brenda A. Wilson
Chad M. Rienstra
Biomolecular NMR Assignments, 2014, 8 : 221 - 224
[29] Backbone and side-chain chemical shift assignments of the kringle domain of human receptor tyrosine kinase-like orphan receptor 1 (ROR1)
Ma, Xiaofang
Zhang, Yingying
Liu, Bin
Yang, Jiahui
Hu, Kaifeng
BIOMOLECULAR NMR ASSIGNMENTS, 2018, 12 (01) : 145 - 148
[30] Backbone and side-chain chemical shift assignments of the kringle domain of human receptor tyrosine kinase-like orphan receptor 1 (ROR1)
Xiaofang Ma
Yingying Zhang
Bin Liu
Jiahui Yang
Kaifeng Hu
Biomolecular NMR Assignments, 2018, 12 : 145 - 148

← 1 2 3 4 5 →