Pharmacotherapy in the Critically Ill Obese Patient

被引：25

作者：

Medico, Charles J. ^{[1
,2
]}

Walsh, Patrick ^{[3
,4
,5
]}

机构：

[1] Geisinger Med Ctr, Div Syst Therapeut & Crit Care Med, Danville, PA 17822 USA

[2] Wilkes Univ, Nesbitt Coll Pharm & Nursing, Dept Pharm Practice, Wilkes Barre, PA 18766 USA

[3] Geisinger Med Ctr, Div Crit Care Med, Danville, PA 17822 USA

[4] Temple Univ, Sch Med, Dept Med, Philadelphia, PA 19140 USA

[5] Temple Univ, Sch Med, Dept Surg, Philadelphia, PA 19140 USA

来源：

CRITICAL CARE CLINICS | 2010年 / 26卷 / 04期

关键词：

Pharmacotherapy; Obese; Dosing; Body weight; PARTIAL THROMBOPLASTIN TIME; BODY-MASS INDEX; MORBIDLY OBESE; VENOUS THROMBOEMBOLISM; CLINICAL PHARMACIST; ECONOMIC OUTCOMES; HEPARIN-THERAPY; WEIGHT; PHARMACOKINETICS; PHARMACODYNAMICS;

D O I：

10.1016/j.ccc.2010.07.003

中图分类号：

R4 [临床医学];

学科分类号：

1002 ; 100602 ;

摘要：

Despite the growing epidemic of obesity in the United States dosing medications in such patients remains poorly studied and understood Most recommendations are based on small independent studies case reports and expert opinion Applying manufacturer kinetics and dosing recommendations in the obese patient may result in toxicity or treatment failure leading to increased morbidity, mortality, and hospital length of stay

引用

页码：679 / +

页数：11

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