One-step construction of hierarchical Ni(OH)2/RGO/Cu2O on Cu foil for ultra-sensitive non-enzymatic glucose and hydrogen peroxide detection

A hierarchized Ni(OH)(2)/RGO/Cu2O nanocomposite electrode grown on Cu foil was prepared through a facile in-situ one-pot hydrothermal method. Three kinds of strong interfaces of Ni(OH)(2)/RGO, RGO/Cu2O and Cu2O/Cu were simultaneously formed and thus a sandwich structure of Ni(OH)(2)/RGO/Cu2O was constructed on Cu substrate. Without further assembly and modification, as-synthesized Ni(OH)(2)/RGO/Cu2O@Cu was directly used as a non-enzymatic sensor, which exhibited a better amperometric response than other non-enzymatic sensors, e.g., detection limit (0.35 mu M and 0.20 mu M), sensitivity (5350 uA.mM(-1).cm(-2) and 1706.3 uA.mM(-1).cm(-2)) and linear range (0.5 mu M to 7.67 and 7.5 mM) on the detection of glucose and hydrogen peroxide. Furthermore, the non-enzymatic sensor showed good long-term stability and good performance in human blood analysis. The present work gives a new insight in sensor based on metal hydroxide/RGO/metal oxides electrode and its potential application in non-enzymatic glucose and hydrogen peroxide sensing.