affinity based screening;
cellular imaging;
high-throughput screening;
D O I:
10.1517/17460441.1.3.195
中图分类号:
R9 [药学];
学科分类号:
1007 ;
摘要:
The last decade showed a further upsurge in screening technology advance and innovation. Notably, the establishment of ultra high-throughput screening facilities led to an explosion of screening capacities. However, in the last 2 years, a turning point in screening philosophy can be observed worldwide. Increasingly more companies are reducing the size of screening campaigns, while increasing the emphasis on data quality and relevance. This article tries to investigate how screening technologies will develop in the ever-changing landscape of drug discovery.
机构:
Univ Madras, CAS Crystallog & Biophys, Guindy Campus, Chennai 600025, Tamil Nadu, IndiaUniv Madras, CAS Crystallog & Biophys, Guindy Campus, Chennai 600025, Tamil Nadu, India
Velmurugan, Devadasan
Pachaiappan, R.
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机构:
SRM Inst Sci & Technol, Dept Biotechnol, Kattankulathur 603203, Tamil Nadu, IndiaUniv Madras, CAS Crystallog & Biophys, Guindy Campus, Chennai 600025, Tamil Nadu, India
Pachaiappan, R.
Ramakrishnan, Chandrasekaran
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h-index: 0
机构:
Indian Inst Technol IIT Madras, Bhupat & Jyoti Mehta Sch Biosci, Dept Biotechnol, Chennai 600036, Tamil Nadu, IndiaUniv Madras, CAS Crystallog & Biophys, Guindy Campus, Chennai 600025, Tamil Nadu, India