Recent Advances in the Direct Nucleophilic Substitution of Allylic Alcohols through SN1-Type Reactions

被引：91

作者：

Baeza, Alejandro ^{[1
]}

Najera, Carmen

机构：

[1] Univ Alicante, Dept Quim Organ, E-03080 Alicante, Spain

来源：

SYNTHESIS-STUTTGART | 2014年 / 46卷 / 01期

关键词：

S(N)1 reaction; allylic substitution; carbocations; allylic alcohols; green chemistry; PI-ACTIVATED ALCOHOLS; CATALYZED DIRECT SUBSTITUTION; FRIEDEL-CRAFTS ALKYLATION; BETA-DICARBONYL COMPOUNDS; C BOND FORMATION; HYDROXY GROUP; FLUORINATED ALCOHOLS; 1,3-DICARBONYL COMPOUNDS; HETEROATOM NUCLEOPHILES; HOMOGENEOUS CATALYSIS;

D O I：

10.1055/s-0033-1340316

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Direct nucleophilic substitution reactions of allylic alcohols are environmentally friendly, since they generate only water as a byproduct, allowing access to new allylic compounds. This reaction has, thus, attracted the interest of the chemical community and several strategies have been developed for its successful accomplishment. This review gathers the latest advances in this methodology involving S(N)1-type reactions. 1Introduction 2S(N)1-Type Direct Nucleophilic Substitution Reactions of Allylic Alcohols 2.1Lewis Acids as Catalysts 2.2BrOnsted Acids as Catalysts 2.3Other Promoters 3Conclusions and Outlook

引用

页码：25 / 34

页数：10

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