Complex trait genetics the role of mechanistic - "Intermediate phenotypes" and candidate genetic loci

被引：2
|
作者：
Rao, Fangwen [1 ,2 ,3 ]
O'Connor, Daniel T. [1 ,2 ,3 ]
机构：
[1] Univ Calif San Diego, Ctr Human Genet & Gen, Dept Pharmacol, La Jolla, CA 92093 USA
[2] Univ Calif San Diego, Ctr Human Genet & Gen, Dept Pharmacol, La Jolla, CA 92093 USA
[3] Vet Adm San Diego Healthcare Syst, San Diego, CA USA
来源：
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY | 2008年 / 52卷 / 02期
关键词：
D O I：
10.1016/j.jacc.2008.02.080
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
引用
收藏
页码：166 / 168
页数：3
相关论文
共 50 条
  • [21] Adrenal gland tumorigenesis after gonadectomy in mice is a complex genetic trait driven by epistatic loci
    Bernichtein, Sophie
    Petretto, Enrico
    Jamieson, Stacey
    Goel, Anuj
    Aitman, Timothy J.
    Mangion, Jonathan M.
    Huhtaniemi, Ilpo T.
    [J]. ENDOCRINOLOGY, 2008, 149 (02) : 651 - 661
  • [22] Genetic dissection of tocopherol content and composition in maize grain using quantitative trait loci analysis and the candidate gene approach
    Subhash Chander
    Y. Q. Guo
    X. H. Yang
    J. B. Yan
    Y. R. Zhang
    T. M. Song
    J. S. Li
    [J]. Molecular Breeding, 2008, 22
  • [23] Genetic dissection of tocopherol content and composition in maize grain using quantitative trait loci analysis and the candidate gene approach
    Chander, Subhash
    Guo, Y. Q.
    Yang, X. H.
    Yan, J. B.
    Zhang, Y. R.
    Song, T. M.
    Li, J. S.
    [J]. MOLECULAR BREEDING, 2008, 22 (03) : 353 - 365
  • [24] Genetic Susceptibility to Therapy-Related Leukemia - Role of Expression Quantitative Trait Loci (eQTL)
    Ding, Yan
    Sun, Can-Lan
    Francisco, Liton
    Li, Liang
    Li, Min
    Hahn, Brian
    Noe, Jennifer
    Larson, Garrett P.
    Forman, Stephen J.
    Bhatia, Ravi
    Bhatia, Smita
    [J]. BLOOD, 2011, 118 (21) : 1047 - 1048
  • [25] A brain-wide genome-wide association study of candidate quantitative trait loci associated with structural and functional phenotypes of pain sensitivity
    Zhang, Li
    Pan, Yiwen
    Huang, Gan
    Liang, Zhen
    Li, Linling
    Zhang, Min
    Zhang, Zhiguo
    [J]. CEREBRAL CORTEX, 2023, 33 (11) : 7297 - 7309
  • [26] Genetic mapping of quantitative trait loci underlying complex genotype-phenotype relationships in forest trees
    Wu, R
    Han, Y
    [J]. SILVAE GENETICA, 1999, 48 (3-4) : 133 - 146
  • [27] Neuropsychological and dimensional behavioral trait profiles in Costa Rican ADHD sib pairs: Potential intermediate phenotypes for genetic studies
    Peskin, Viviana A.
    Ordonez, Anna
    Mackin, R. Scott
    Delucchi, Kevin
    Monge, Silvia
    McGough, James J.
    Chavira, Denise A.
    Berrocal, Monica
    Cheung, Erika
    Fournier, Eduardo
    Badner, Judith A.
    Herrera, Luis Diego
    Mathews, Carol A.
    [J]. AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS, 2015, 168 (04) : 247 - 257
  • [28] THE ROLE OF COMMON GENETIC VARIATION AROUND SIX CANDIDATE LOCI FOR SUSCEPTIBILITY TO INTRAHEPATIC CHOLESTASIS OF PREGNANCY
    Dixon, Peter H.
    Wadsworth, Christopher A.
    Chambers, Jennifer
    Donnelly, Jennifer
    Cooley, Sharon M.
    Jarvis, Sheba
    Kubitz, Ralf
    Lammert, Frank
    Marschall, Hanns-Ulrich
    Glantz, Anna
    Khan, Shahid A.
    Whittaker, John
    Geary, Michael
    Williamson, Catherine
    [J]. HEPATOLOGY, 2010, 52 (04) : 479A - 479A
  • [29] Alcoholism as a complex trait: Comparison of genetic models and role of epidemiological risk factors
    Macciardi, F
    Morenghi, E
    Morabito, A
    [J]. GENETIC EPIDEMIOLOGY, 1999, 17 : S247 - S252
  • [30] Genetic control of RNA splicing and its distinct role in complex trait variation
    Ting Qi
    Yang Wu
    Hailing Fang
    Futao Zhang
    Shouye Liu
    Jian Zeng
    Jian Yang
    [J]. Nature Genetics, 2022, 54 : 1355 - 1363
12345