Monomeric actin required for INO80 remodeling

被引：8
|
作者：
Bartholomew, Blaine [1 ]
机构：
[1] So Illinois Univ, Sch Med, Carbondale, IL 62901 USA
来源：
NATURE STRUCTURAL & MOLECULAR BIOLOGY | 2013年 / 20卷 / 04期
关键词：
NUCLEAR ACTIN; BETA-ACTIN; CHROMATIN; TRANSCRIPTION; COMPLEX; BINDING;
D O I：
10.1038/nsmb.2553
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Nuclear actin is a subunit of several chromatin-remodeling complexes, and the efficient binding of INO80 to extranucleosomal DNA is now shown to require actin. The form of actin present in the INO80 complex is monomeric and cannot associate with actin filaments.
引用
收藏
页码：405 / 407
页数：3
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